The query sequence for this search has been filtered. Filtering
eliminates low complexity regions that commonly give spuriously high
scores that reflect compositional bias rather than significant
position-by-position alignment. Filtering can eliminate these potentially
confounding matches (e.g., hits against proline-rich regions or poly-A
tails) from the blast reports, leaving regions whose blast statistics
reflect the specificity of their pairwise alignment.

BLASTX 2.2.1 [Apr-13-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Fgr_contig0014.seq Fgr_contig0014
         (1407 letters)

Database: nr
           705,144 sequences; 222,175,239 total letters


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

emb|CAC28831.1|  (AL513467) probable protein disulfide-isome...   441  e-123
sp|Q92249|ER38_NEUCR  PUTATIVE DISULFIDE ISOMERASE ERP38 PRE...   441  e-123
sp|Q00216|TIGA_ASPNG  PUTATIVE DISULFIDE ISOMERASE TIGA PREC...   420  e-116
gb|AAB86685.1|  (AF019112) protein disulfide isomerase; PDI;...   237  2e-61
sp|O13811|PDI2_SCHPO  PUTATIVE PROTEIN DISULFIDE ISOMERASE C...   231  8e-60
sp|O22263|PDA6_ARATH  PROBABLE PROTEIN DISULFIDE ISOMERASE A...   225  6e-58
sp|P38661|ERP5_MEDSA  PROBABLE PROTEIN DISULFIDE ISOMERASE P...   222  5e-57
pir||T03644  probable protein disulfide-isomerase (EC 5.3.4....   221  1e-56
gb|AAK50038.2|  (AF363787) protein disulfide isomerase famil...   181  1e-44
gb|AAF45013.1|AE003406_218  (AE003416) symbol=BG:DS09218.4; ...   172  8e-42
sp|P38660|PDA6_MESAU  PROTEIN DISULFIDE ISOMERASE A6 PRECURS...   159  5e-38
sp|Q63081|PDA6_RAT  PROTEIN DISULFIDE ISOMERASE A6 PRECURSOR...   159  7e-38
dbj|BAB24354.1|  (AK005989) putative [Mus musculus]               157  2e-37
gb|AAH06865.1|AAH06865  (BC006865) Similar to protein disulf...   157  2e-37
ref|NP_005733.1|  protein disulfide isomerase-related protei...   156  3e-37
gb|AAB50217.1|  (U79278) protein disulfide isomerase-related...   156  4e-37
gb|AAF40463.1|AC004809_21  (AC004809) Strong simialrity to t...   153  4e-36
gb|AAF48082.2|  (AE003487) CG1837 gene product [Drosophila m...   148  9e-35
pir||T01115  hypothetical protein T21L14.14 - Arabidopsis th...   147  3e-34
sp|P34329|PDA4_CAEEL  PROBABLE PROTEIN DISULFIDE ISOMERASE A...   144  1e-33
pir||S44756  probable protein disulfide-isomerase (EC 5.3.4....   144  1e-33
pir||T27039  hypothetical protein Y49E10.4 - Caenorhabditis ...   139  6e-32
sp|Q11067|PDA6_CAEEL  PROBABLE PROTEIN DISULFIDE ISOMERASE A...   137  2e-31
ref|NP_004902.1|  protein disulfide isomerase related protei...   133  4e-30
ref|NP_110437.1|  hypothetical protein MGC3178 [Homo sapiens...   130  2e-29
gb|AAC37215.1|  (L28174) disulfide-like protein [Acanthamoeb...   130  3e-29
ref|NP_006801.1|  for protein disulfide isomerase-related [H...   129  6e-29
sp|P38659|PDA4_RAT  PROTEIN DISULFIDE ISOMERASE A4 PRECURSOR...   127  3e-28
pir||S32476  protein disulfide-isomerase (EC 5.3.4.1) ERp72 ...   127  3e-28
ref|NP_033917.1|  calcium binding protein, intestinal; endop...   126  4e-28
sp|P08003|PDA4_MOUSE  PROTEIN DISULFIDE ISOMERASE A4 PRECURS...   126  4e-28
gb|AAH09151.1|AAH09151  (BC009151) Similar to for protein di...   125  8e-28
gb|AAF53293.1|  (AE003639) CG9302 gene product [Drosophila m...   125  1e-27
gb|AAG13988.1|AF298829_1  (AF298829) putative protein disulf...   117  3e-25
ref|XP_002849.3|  for protein disulfide isomerase-related [H...   109  5e-23
pir||S71862  protein disulfide-isomerase (EC 5.3.4.1) precur...   102  6e-21
pir||T34092  hypothetical protein C07A12.4 - Caenorhabditis ...   102  6e-21
pir||ISMSSS  protein disulfide-isomerase (EC 5.3.4.1) precur...   101  1e-20
sp|P09103|PDI_MOUSE  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...   101  2e-20
emb|CAA31502.1|  (X13110) prolyl-4-hydroxylase (AA 5 - 494) ...   100  2e-20
pir||ISCHSS  protein disulfide-isomerase (EC 5.3.4.1) precur...   100  2e-20
sp|P09102|PDI_CHICK  PROTEIN DISULFIDE ISOMERASE (PDI) (PROL...   100  2e-20
dbj|BAB55307.1|  (AK027701) unnamed protein product [Homo sa...   100  3e-20
gb|AAA85099.1|  (U12440) protein disulfide isomerase [Onchoc...   100  3e-20
gb|AAA61169.1|  (J02783) thyroid hormone binding protein pre...   100  5e-20
sp|P04785|PDI_RAT  PROTEIN DISULFIDE ISOMERASE PRECURSOR (PD...   100  5e-20
gb|AAA40620.1|  (M21018) iodothyronine 5' monodeiodinase [Ra...   100  5e-20
sp|P05307|PDI_BOVIN  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...   100  5e-20
pir||T46333  hypothetical protein DKFZp434J1813.1 - human (f...    99  6e-20
dbj|BAB55121.1|  (AK027450) unnamed protein product [Homo sa...    99  6e-20
sp|P07237|PDI_HUMAN  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    99  6e-20
sp|P21195|PDI_RABIT  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    99  6e-20
dbj|BAB55263.1|  (AK027647) unnamed protein product [Homo sa...    99  6e-20
dbj|BAB55304.1|  (AK027696) unnamed protein product [Homo sa...    99  8e-20
pdb|1MEK|     Human Protein Disulfide Isomerase, Nmr, 40 Str...    99  1e-19
gb|AAH02207.1|AAH02207  (BC002207) Unknown (protein for IMAG...    98  2e-19
dbj|BAB23413.1|  (AK004617) putative [Mus musculus]                98  2e-19
emb|CAC21229.1|  (AJ277378) protein disulfide isomerase [Tri...    97  2e-19
gb|AAD55566.1|AF110784_1  (AF110784) protein disulfide isome...    97  2e-19
gb|AAK49424.1|AF262980_1  (AF262980) protein disulfide isome...    97  2e-19
emb|CAC21228.1|  (AJ277377) protein disulfide isomerase [Tri...    97  2e-19
gb|AAK49425.1|AF262981_1  (AF262981) protein disulfide isome...    97  2e-19
sp|P52589|PDI_WHEAT  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    97  2e-19
ref|NP_037130.1|  protein disulfide isomerase  (Prolyl 4-hyd...    97  3e-19
pir||T07927  protein disulfide-isomerase (EC 5.3.4.1) RB60 -...    95  1e-18
emb|CAC28361.2|  (AJ306291) putative protein disulfide isome...    95  1e-18
ref|NP_000909.1|  procollagen-proline, 2-oxoglutarate 4-diox...    95  1e-18
pir||T23055  hypothetical protein H06O01.1 - Caenorhabditis ...    95  1e-18
gb|AAF58609.1|  (AE003824) CG8983 gene product [Drosophila m...    95  2e-18
sp|P80284|PDI_HORVU  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    95  2e-18
ref|XP_011568.2|  11469 [Homo sapiens]                             94  2e-18
pir||S68280  protein disulfide-isomerase (EC 5.3.4.1) ERp60 ...    94  2e-18
sp|P54399|PDI_DROME  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    94  3e-18
pir||S71863  protein disulfide-isomerase (EC 5.3.4.1) isofor...    94  3e-18
dbj|BAA92322.1|  (AB039278) protein disulfide isomerase [Ory...    93  5e-18
pir||T26967  hypothetical protein Y47H9C.5 - Caenorhabditis ...    93  6e-18
gb|AAC77456.1|  (AF095899) PDI related protein A [Aspergillu...    93  6e-18
emb|CAB40200.1|  (AJ005807) disulphide isomerase [Caenorhabd...    92  8e-18
emb|CAA12644.1|  (AJ225804) protein disulphide isomerase [Fa...    92  8e-18
sp|Q9XF61|PDI_DATGL  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    92  1e-17
gb|AAG45936.1|AF325211_1  (AF325211) protein disulfide isome...    92  1e-17
sp|Q10057|PDI1_SCHPO  PUTATIVE PROTEIN DISULFIDE ISOMERASE C...    92  1e-17
emb|CAA10978.1|  (AJ222773) protein disulphide isomerase [Hy...    92  1e-17
sp|P55059|PDI_HUMIN  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    92  1e-17
sp|P52588|PDI_MAIZE  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    92  1e-17
sp|P29828|PDI_MEDSA  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    91  2e-17
dbj|BAA99572.1|  (AB036825) thioredoxin [Chlorella vulgaris]       91  2e-17
gb|AAG22829.1|AF306866_1  (AF306866) putative disulfide-isom...    91  3e-17
gb|AAK61223.1|AE006463_3  (AE006463) protein disulfide isome...    90  4e-17
ref|NP_006840.1|  protein disulfide isomerase [Homo sapiens]...    90  4e-17
gb|AAH00537.1|AAH00537  (BC000537) Unknown (protein for IMAG...    90  4e-17
pir||A54757  protein disulfide-isomerase (EC 5.3.4.1) / ER c...    90  5e-17
dbj|BAA36352.1|  (AB022013) protein disulphide isomerase lik...    90  5e-17
pir||A41440  protein disulfide-isomerase (EC 5.3.4.1) precur...    90  5e-17
sp|Q9XI01|PDI1_ARATH  PROBABLE PROTEIN DISULFIDE ISOMERASE 1...    90  5e-17
pir||S34275  protein disulfide-isomerase homolog precursor -...    89  9e-17
gb|AAA72723.1|  (M23880) [Chicken prolyl 4-hydroxylase beta-...    89  1e-16
emb|CAC33587.1|  (AJ302014) protein disulphide isomerase [Pi...    87  3e-16
gb|AAA34848.1|  (M62815) protein disulfide isomerase [Saccha...    87  3e-16
pir||A30007  dolichyl-diphosphooligosaccharide--protein glyc...    87  3e-16
sp|Q43116|PDI_RICCO  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    87  3e-16
gb|AAA70346.1|  (L33252) disulfide isomerase [Hordeum vulgare]     87  3e-16
ref|XP_007939.2|  protein disulfide isomerase [Homo sapiens]       87  4e-16
gb|AAC78302.1|  (AF064591) protein disulfide isomerase [Schi...    87  4e-16
sp|Q00248|PDI_ASPOR  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    86  6e-16
emb|CAA36550.1|  (X52313) precursor TRG1 protein [Saccharomy...    86  1e-15
gb|AAF89535.1|AF164624_1  (AF164624) protein disulfide isome...    85  1e-15
emb|CAA38402.1|  (X54535) protein disulphide  isomerase [Sac...    85  1e-15
ref|NP_009887.1|  protein disulfide isomerase; Pdi1p [Saccha...    85  1e-15
dbj|BAB09837.1|  (AB005246) protein disulphide isomerase-lik...    85  2e-15
sp|Q9SRG3|PDI2_ARATH  PROBABLE PROTEIN DISULFIDE ISOMERASE 2...    85  2e-15
gb|AAH03285.1|AAH03285  (BC003285) Similar to ER-60 protease...    84  3e-15
pir||A47300  cell adhesion protein retina cognin - chicken (...    84  4e-15
pir||JC2385  protein disulfide-isomerase (EC 5.3.4.1) ER60 p...    84  4e-15
sp|P11598|PDA3_RAT  PROTEIN DISULFIDE ISOMERASE A3 PRECURSOR...    84  4e-15
sp|P38657|PDA3_BOVIN  PROTEIN DISULFIDE ISOMERASE A3 PRECURS...    84  4e-15
ref|NP_059015.1|  ER-60 protease [Rattus norvegicus] >gi|927...    84  4e-15
prf||2121473A  microsomal protease ER-60 [Oryctolagus cunicu...    84  4e-15
ref|XP_016522.1|  similar to PROTEIN DISULFIDE ISOMERASE A3 ...    83  6e-15
gb|AAC24752.1|  (AF008300) transglutaminase precursor [Dirof...    83  6e-15
sp|P30101|PDA3_HUMAN  PROTEIN DISULFIDE ISOMERASE A3 PRECURS...    83  6e-15
dbj|BAA03759.1|  (D16234) PLC alfa [Homo sapiens]                  83  6e-15
ref|NP_005304.1|  glucose regulated protein, 58kD [Homo sapi...    83  6e-15
pir||S55507  protein disulfide-isomerase (EC 5.3.4.1) ER60 p...    83  6e-15
pir||JC5704  protein disulfide-isomerase (EC 5.3.4.1) ER60 p...    83  6e-15
pir||S63994  protein disulfide-isomerase (EC 5.3.4.1) ER60 p...    83  6e-15
pir||S41661  protein disulfide-isomerase (EC 5.3.4.1) ERp61 ...    82  1e-14
sp|P12244|GSBP_CHICK  DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE-PROT...    82  1e-14
ref|NP_113768.1|  glucose regulated protein, 58 kDa [Rattus ...    82  1e-14
sp|Q12730|PDI_ASPNG  PROTEIN DISULFIDE ISOMERASE PRECURSOR (...    82  1e-14
emb|CAC15387.1|  (AJ250363) putative disulfide isomerase [Pl...    82  1e-14
gb|AAK27796.1|AF295634_1  (AF295634) protein disulfide isome...    81  2e-14
sp|P38658|ER60_SCHMA  PROBABLE PROTEIN DISULFIDE ISOMERASE E...    81  2e-14
emb|CAA30112.1|  (X07077) glutathione-insulin transhydrogena...    80  4e-14
ref|XP_008588.3|  procollagen-proline, 2-oxoglutarate 4-diox...    80  4e-14
ref|NP_031978.1|  glucose regulated protein, 58 kDa; endopla...    80  5e-14
pir||T37630  protein disulfide-isomerase (EC 5.3.4.1) precur...    79  7e-14
prf||2006292A  thioredoxin [Streptomyces aureofaciens]             79  9e-14
gb|AAA72728.1|  (M23880) prolyl 4-hydroxylase beta-subunit [...    79  1e-13
gb|AAF78087.1|AF274502_2  (AF274502) protein disulfide isome...    79  1e-13
ref|XP_016515.1|  glucose regulated protein, 58kD [Homo sapi...    79  1e-13
pir||JC5378  protein disulfide-isomerase (EC 5.3.4.1) - Cryp...    78  2e-13
gb|AAD42032.1|AF075246_1  (AF075246) protein disulfide isome...    77  3e-13
dbj|BAB47459.1|  (AB058733) KIAA1830 protein [Homo sapiens]        77  4e-13
gb|AAF20171.1|  (AF164117) protein disulfide isomerase 3 [Gi...    77  4e-13
sp|P33791|THIO_STRAU  THIOREDOXIN (TRX) >gi|421638|pir||S333...    77  4e-13
dbj|BAB28225.1|  (AK012415) putative [Mus musculus]                76  8e-13
emb|CAB51612.1|  (AJ243958) protein disulfide isomerase [Klu...    75  1e-12
gb|AAF40013.1|  (AC006834) contains similarity to Pfam famil...    75  2e-12
gb|AAG21333.1|AF273730_1  (AF273730) hypothetical esophageal...    74  2e-12
sp|P56430|THIO_HELPY  THIOREDOXIN (TRX) >gi|7430827|pir||H64...    74  2e-12
sp|P33636|THI2_ECOLI  THIOREDOXIN 2 (TRX2) >gi|7430826|pir||...    74  2e-12
gb|AAB07885.1|  (U63815) similar to protein disulfide isomer...    74  2e-12
sp|P06544|THI1_ANASO  THIOREDOXIN 1 (TRX-1) (THIOREDOXIN M) ...    74  3e-12
ref|XP_007536.3|  similar to PROTEIN DISULFIDE ISOMERASE A3 ...    74  3e-12
gb|AAB63409.2|  (U97402) Hypothetical protein C30H7.2 [Caeno...    74  3e-12
gb|AAD09366.2|  (U65017) protein disulfide isomerase-2 precu...    73  5e-12
sp|P96132|THIO_THIRO  THIOREDOXIN (TRX) >gi|1688093|gb|AAB36...    73  6e-12
pir||G70464  thioredoxin - Aquifex aeolicus >gi|2984180|gb|A...    73  6e-12
pir||E81850  thioredoxin I NMA1578 [imported] - Neisseria me...    72  8e-12
ref|NP_010806.1|  Protein disulfide isomerase homolog; Eug1p...    72  1e-11
sp|P00275|THI1_CORNE  THIOREDOXIN C-1 >gi|65808|pir||TXFK th...    72  1e-11
dbj|BAB24190.1|  (AK005692) putative [Mus musculus]                71  2e-11
sp|Q9X2T1|THIO_PSEAE  THIOREDOXIN (TRX) >gi|11352633|pir||G8...    71  2e-11
sp|P12865|BS2_TRYBB  BLOODSTREAM-SPECIFIC PROTEIN 2 PRECURSO...    70  3e-11
sp|Q41864|THIM_MAIZE  THIOREDOXIN M-TYPE, CHLOROPLAST PRECUR...    70  4e-11
gb|AAF79381.1|AC007887_40  (AC007887) F15O4.20 [Arabidopsis ...    70  4e-11
gb|AAK62431.1|AF386986_1  (AF386986) Unknown protein [Arabid...    70  4e-11
pdb|1XOA|     Thioredoxin (Oxidized Disulfide Form), Nmr, 20...    70  5e-11
sp|P52231|THIO_SYNY3  THIOREDOXIN (TRX) >gi|628912|pir||S469...    70  5e-11
gb|AAA24696.1|  (M54881) thioredoxin [Escherichia coli]            70  5e-11
pir||D82338  thioredoxin VC0306 [imported] - Vibrio cholerae...    70  5e-11
pdb|2TRX|A  Chain A, Thioredoxin >gi|230778|pdb|2TRX|B Chain...    70  5e-11
sp|P00274|THIO_ECOLI  THIOREDOXIN 1 (TRX1) (TRX) >gi|321736|...    70  5e-11
gb|AAA67270.1|  (U16857) Derived from E. coli thioredoxin ge...    70  5e-11
gb|AAA24534.1|  (K02845) thioredoxin [Escherichia coli] >gi|...    70  5e-11
pir||T25574  hypothetical protein C30H7.2 - Caenorhabditis e...    70  5e-11
sp|P52233|THIO_THIFE  THIOREDOXIN (TRX) >gi|664829|gb|AAA889...    69  7e-11
pir||C81090  thioredoxin NMB1366 [imported] - Neisseria meni...    69  9e-11
pir||F82526  thioredoxin XF2698 [imported] - Xylella fastidi...    69  9e-11
sp|Q9ZP20|THIM_ORYSA  THIOREDOXIN M-TYPE, CHLOROPLAST PRECUR...    69  9e-11
pir||A55124  thioredoxin - Chloroflexus aurantiacus                69  1e-10
sp|P46843|TRXB_MYCLE  BIFUNCTIONAL THIOREDOXIN REDUCTASE/THI...    69  1e-10
gb|AAF79823.1|AC026875_3  (AC026875) T6D22.5 [Arabidopsis th...    69  1e-10
pdb|2TIR|     Thioredoxin Mutant With Lys 36 Replaced By Glu...    68  2e-10
ref|NP_105806.1|  thioredoxin [Mesorhizobium loti] >gi|14024...    68  2e-10
sp|P48384|THIM_PEA  THIOREDOXIN M-TYPE, CHLOROPLAST PRECURSO...    68  2e-10
gb|AAC49358.1|  (U35831) thioredoxin m [Pisum sativum]             68  2e-10
gb|AAG23476.1|  (AC084197) Hypothetical protein Y73B6BL.12 [...    68  2e-10
emb|CAA58999.1|  (X84217) proteindisulfidisomerase [Alternar...    68  2e-10
sp|P09857|THIO_CHRVI  THIOREDOXIN (TRX) >gi|79441|pir||A2662...    68  2e-10
prf||2105155A  thioredoxin [Chloroflexus aurantiacus]              67  3e-10
sp|P43785|THIO_HAEIN  THIOREDOXIN (TRX) >gi|1075347|pir||E64...    67  3e-10
ref|NP_014931.1|  Disulfide isomerase related protein; Mpd1p...    67  3e-10
pir||C81432  thioredoxin Cj0147c [imported] - Campylobacter ...    67  4e-10
pir||E83138  probable thioredoxin PA4061 [imported] - Pseudo...    67  4e-10
ref|NP_070112.1|  thioredoxin (trx-3) [Archaeoglobus fulgidu...    67  4e-10
sp|Q9ZP21|THIM_WHEAT  THIOREDOXIN M-TYPE, CHLOROPLAST PRECUR...    67  4e-10
sp|P07591|THIM_SPIOL  THIOREDOXIN M-TYPE, CHLOROPLAST PRECUR...    67  5e-10
emb|CAA35827.1|  (X51463) thioredoxin M precursor (AA -67 to...    67  5e-10
emb|CAA55398.1|  (X78821) thioredoxin m [Chlamydomonas reinh...    67  5e-10
pdb|1DBY|A  Chain A, Nmr Structures Of Chloroplast Thioredox...    67  5e-10
emb|CAA44209.1|  (X62335) thioredoxin  Ch2 [Chlamydomonas re...    67  5e-10
sp|P23400|THIM_CHLRE  THIOREDOXIN M-TYPE, CHLOROPLAST PRECUR...    67  5e-10
pdb|1TXX|A  Chain A, Active-Site Variant Of E.Coli Thioredoxin     66  6e-10
pdb|1FB0|A  Chain A, Crystal Structure Of Thioredoxin M From...    66  8e-10
pdb|1F6M|C  Chain C, Crystal Structure Of A Complex Between ...    66  8e-10
pdb|1THO|     Thioredoxin Mutant With Arg Inserted Between G...    66  8e-10
pir||S10743  thioredoxin - Chlamydomonas reinhardtii               65  1e-09
sp|P12243|THI1_SYNP7  THIOREDOXIN 1 (TRX-1) (THIOREDOXIN M) ...    65  1e-09
sp|P50254|THIO_PORYE  THIOREDOXIN >gi|1086260|pir||S46521 th...    65  1e-09
gb|AAK25501.1|  (AE006012) thioredoxin [Caulobacter crescentus]    65  1e-09
emb|CAB57801.1|  (X06768) protein disulphide isomerase [Gall...    65  1e-09
dbj|BAB22648.1|  (AK003217) putative [Mus musculus]                65  1e-09
dbj|BAB39860.1|  (AB032759) thioredoxin [Actinobacillus acti...    65  2e-09
ref|NP_045133.1|  unknown; thioredoxin [Cyanidium caldarium]...    65  2e-09
sp|Q9SEU8|THM2_ARATH  THIOREDOXIN M-TYPE 2, CHLOROPLAST PREC...    65  2e-09
gb|AAF47072.1|  (AE003462) CG5554 gene product [Drosophila m...    64  2e-09
pir||A28215  thioredoxin - Rhodospirillum rubrum                   64  2e-09
sp|P52229|THIO_MYCTU  THIOREDOXIN (TRX) (MPT46) >gi|7430822|...    64  2e-09
sp|P10473|THIO_RHORU  THIOREDOXIN (TRX)                            64  2e-09
emb|CAB97670.1|  (AL160493) probable protein disulfide isome...    64  2e-09
sp|P50338|THIO_GRIPA  THIOREDOXIN >gi|7430828|pir||S46522 th...    64  3e-09
sp|P80579|THIO_ALIAC  THIOREDOXIN (TRX) >gi|6980431|pdb|1QUW...    64  3e-09
gb|AAK03078.1|  (AE006138) TrxM [Pasteurella multocida]            64  3e-09
sp|P07887|THI2_CORNE  THIOREDOXIN C-2 >gi|80613|pir||S02802 ...    64  4e-09
gb|AAA23305.1|  (J02801) thioredoxin C-2 [Corynebacterium ne...    64  4e-09
pir||G75455  thioredoxin - Deinococcus radiodurans (strain R...    64  4e-09
pir||T06724  protein disulfide-isomerase homolog F28P10.60 -...    64  4e-09
gb|AAF15949.1|AF095750_1  (AF095750) thioredoxin m2 [Arabido...    64  4e-09
ref|NP_053835.1|  thioredoxin [Porphyra purpurea] >gi|172994...    63  5e-09
pir||G75612  thioredoxin 1 - Deinococcus radiodurans (strain...    63  7e-09
sp|P08058|THIO_RHOSH  THIOREDOXIN (TRX) >gi|97533|pir||A3513...    63  7e-09
pir||T42061  thioredoxin - Streptomyces coelicolor >gi|10330...    63  7e-09
ref|NP_106376.1|  thioredoxin [Mesorhizobium loti] >gi|14025...    63  7e-09
sp|P52230|THIO_STRCO  THIOREDOXIN (TRX) >gi|7481797|pir||T36...    63  7e-09
ref|NP_075757.1|  sulfhydryl oxidase [Mus musculus] >gi|1271...    63  7e-09
gb|AAF04439.1|AC010718_8  (AC010718) thioredoxin-like protei...    63  7e-09
gb|AAG53892.1|AF285078_1  (AF285078) FAD-dependent sulfhydry...    63  7e-09
emb|CAB51775.1|  (AJ243960) MPD1 homologue [Kluyveromyces la...    62  9e-09
sp|O51088|THIO_BORBU  THIOREDOXIN (TRX) >gi|7430839|pir||E70...    62  9e-09
dbj|BAA25499.1|  (AB011145) KIAA0573 protein [Homo sapiens]        62  9e-09
gb|AAH05374.1|AAH05374  (BC005374) Similar to RIKEN cDNA 111...    62  9e-09
gb|AAD39273.1|AC007203_5  (AC007203) Hypothetical protein [A...    62  1e-08
gb|AAF35402.1|  (AC024081) thioredoxin m4 [Arabidopsis thali...    62  1e-08
sp|P52232|THI1_SYNY3  THIOREDOXIN-LIKE PROTEIN SLR0233 >gi|7...    62  1e-08
sp|Q9XGS0|THIM_BRANA  THIOREDOXIN M-TYPE, CHLOROPLAST PRECUR...    62  1e-08
pir||B82423  thioredoxin 2 VCA0752 [imported] - Vibrio chole...    62  1e-08
gb|AAF15952.1|AF095753_1  (AF095753) thioredoxin x [Arabidop...    62  1e-08
gb|AAD50039.1|AC007980_4  (AC007980) Similar to thioredoxin ...    62  1e-08

>emb|CAC28831.1| (AL513467) probable protein disulfide-isomerase precursor [Neurospora
            crassa]
          Length = 369

 Score =  441 bits (1135), Expect = e-123
 Identities = 216/358 (60%), Positives = 260/358 (72%)
 Frame = -3

Query: 1297 MVLIKSFVLGXXXXXXXXXXAVIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVW 1118
            MVL+KS V+           AV++L+PSNFDD+VLKSGKPTLVEFFAPWCGHCK LAPV+
Sbjct: 1    MVLLKSLVVASLAAAVAAKSAVLDLIPSNFDDVVLKSGKPTLVEFFAPWCGHCKNLAPVY 60

Query: 1117 EDLANTYESAKGKVQIAKVDADAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLES 938
            E+LA   E AK KVQIAKVDADA R LGKRFG+QGFPTLKFFDGKS +P +YK GRDL+S
Sbjct: 61   EELATALEYAKDKVQIAKVDADAERALGKRFGVQGFPTLKFFDGKSEQPVDYKGGRDLDS 120

Query: 937  LTTFIAEKTGVKSKKKLEMPSEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTW 758
            L+ FIAEKTGVK++KK   PS V  LNDAT    +G DK++LVAFTAPWCGHCK LAPTW
Sbjct: 121  LSNFIAEKTGVKARKKGSAPSLVNILNDATIKGAIGGDKNVLVAFTAPWCGHCKNLAPTW 180

Query: 757  EDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQ 578
            E LAATFA+D  + IAKVDA+AP  K +A + GV  +PTIK+FP GS     Y  GR+E 
Sbjct: 181  EKLAATFASDPEITIAKVDADAPTGKKSAAEYGVSGFPTIKFFPKGSTTPEDYNGGRSEA 240

Query: 577  AFVDWINEKAGTHRVVGGGLDNVAGTVESLDTLVAKXXXXXXXXXXXXXXXXXXEGLTDA 398
              V ++NEKAGTHR  GGGLD VAGT+ +LD +VAK                  + L ++
Sbjct: 241  DLVKFLNEKAGTHRTPGGGLDTVAGTIAALDEIVAKYTGGASLAEVAEEAKEAVKSLKNS 300

Query: 397  AQKTYAEYYVRVFDKLSSNNDWVSKELGRLDGILAKGGLAPSKRDQIQQKTNVLRKFV 224
            A+  YA+YY+RV DKLS +  + +KE  RL+GIL KGGLAP+K D++  K NVLRKFV
Sbjct: 301  AELKYADYYLRVLDKLSKSEGYATKEFARLEGILKKGGLAPAKVDELTVKVNVLRKFV 358



>sp|Q92249|ER38_NEUCR PUTATIVE DISULFIDE ISOMERASE ERP38 PRECURSOR
 pir||T47259 probable protein disulfide-isomerase (EC 5.3.4.1) precursor
            [imported] - Neurospora crassa
 emb|CAA68847.1| (Y07562) ERp38 [Neurospora crassa]
          Length = 369

 Score =  441 bits (1134), Expect = e-123
 Identities = 216/358 (60%), Positives = 260/358 (72%)
 Frame = -3

Query: 1297 MVLIKSFVLGXXXXXXXXXXAVIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVW 1118
            MVL+KS V+           AV++L+PSNFDD+VLKSGKPTLVEFFAPWCGHCK LAPV+
Sbjct: 1    MVLLKSLVVASLAAAVAAKSAVLDLIPSNFDDVVLKSGKPTLVEFFAPWCGHCKNLAPVY 60

Query: 1117 EDLANTYESAKGKVQIAKVDADAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLES 938
            E+LA   E AK KVQIAKVDADA R LGKRFG+QGFPTLKFFDGKS +P +YK GRDL+S
Sbjct: 61   EELATALEYAKDKVQIAKVDADAERALGKRFGVQGFPTLKFFDGKSEQPVDYKGGRDLDS 120

Query: 937  LTTFIAEKTGVKSKKKLEMPSEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTW 758
            L+ FIAEKTGVK++KK   PS V  LNDAT    +G DK++LVAFTAPWCGHCK LAPTW
Sbjct: 121  LSNFIAEKTGVKARKKGSAPSLVNILNDATIKGPIGGDKNVLVAFTAPWCGHCKNLAPTW 180

Query: 757  EDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQ 578
            E LAATFA+D  + IAKVDA+AP  K +A + GV  +PTIK+FP GS     Y  GR+E 
Sbjct: 181  EKLAATFASDPEITIAKVDADAPTGKKSAAEYGVSGFPTIKFFPKGSTTPEDYNGGRSEA 240

Query: 577  AFVDWINEKAGTHRVVGGGLDNVAGTVESLDTLVAKXXXXXXXXXXXXXXXXXXEGLTDA 398
              V ++NEKAGTHR  GGGLD VAGT+ +LD +VAK                  + L ++
Sbjct: 241  DLVKFLNEKAGTHRTPGGGLDTVAGTIAALDEIVAKYTGGASLAEVAEEAKEAVKSLKNS 300

Query: 397  AQKTYAEYYVRVFDKLSSNNDWVSKELGRLDGILAKGGLAPSKRDQIQQKTNVLRKFV 224
            A+  YA+YY+RV DKLS +  + +KE  RL+GIL KGGLAP+K D++  K NVLRKFV
Sbjct: 301  AELKYADYYLRVLDKLSKSEGYATKEFARLEGILKKGGLAPAKVDELTVKVNVLRKFV 358



>sp|Q00216|TIGA_ASPNG PUTATIVE DISULFIDE ISOMERASE TIGA PRECURSOR
 emb|CAA67299.1| (X98748) tigA [Aspergillus niger]
          Length = 359

 Score =  420 bits (1080), Expect = e-116
 Identities = 204/337 (60%), Positives = 248/337 (73%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V++L+P NFDD+VLKSGKP LVEFFAPWCGHCK LAPV+E+L   +  A  KV + KVDA
Sbjct: 21   VVDLVPKNFDDVVLKSGKPALVEFFAPWCGHCKNLAPVYEELGQAFAHASDKVTVGKVDA 80

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPS 875
            D HR+LG++FG+QGFPTLK+FDGKS +PE+YK GRDLESL++FI+EKTGVK +   + PS
Sbjct: 81   DEHRDLGRKFGVQGFPTLKWFDGKSDEPEDYKGGRDLESLSSFISEKTGVKPRGPKKEPS 140

Query: 874  EVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDAE 695
            +V  LNDATF   VG D  +LVAFTAPWCGHCK LAPTWE LA  F  + NVVIAKVDA+
Sbjct: 141  KVEMLNDATFKGAVGGDNDVLVAFTAPWCGHCKNLAPTWEALANDFVLEPNVVIAKVDAD 200

Query: 694  APNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGTHRVVGGGLD 515
            A N KATA +QGV  YPTIK+FP GS E+V YE  R+EQAF+D++NEK GTHR VGGGLD
Sbjct: 201  AENGKATAREQGVSGYPTIKFFPKGSTESVPYEGARSEQAFIDFLNEKTGTHRTVGGGLD 260

Query: 514  NVAGTVESLDTLVAKXXXXXXXXXXXXXXXXXXEGLTDAAQKTYAEYYVRVFDKLSSNND 335
              AGT+ SLD L+A                      T+   K YA+YYV+V DKLS N +
Sbjct: 261  TKAGTIASLDELIASTSAADLAAAVKKAA-------TELKDK-YAQYYVKVADKLSQNAE 312

Query: 334  WVSKELGRLDGILAKGGLAPSKRDQIQQKTNVLRKFV 224
            + +KEL RL+ ILAKGG AP K D +  ++N+LRKFV
Sbjct: 313  YAAKELARLEKILAKGGSAPEKVDDLISRSNILRKFV 349



>gb|AAB86685.1| (AF019112) protein disulfide isomerase; PDI; P5-like [Dictyostelium
            discoideum]
          Length = 363

 Score =  237 bits (604), Expect = 2e-61
 Identities = 137/336 (40%), Positives = 195/336 (57%), Gaps = 9/336 (2%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L P NFD +V    K   V+F+APWCGHCKKLAP +E LA+T+     KV IAKVD 
Sbjct: 24   VVVLSPDNFDTVV-DGSKTVFVKFYAPWCGHCKKLAPDFEILADTFAPVSNKVVIAKVDC 82

Query: 1054 DA--HRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAE--KTGVKSKKKL 887
            D   ++ L  ++ + G+PTLK FD KS   ++Y   R ++ L T+I    KT VK KK  
Sbjct: 83   DQADNKALCSKYDVSGYPTLKIFD-KSTTAKDYNGARSVDELLTYINNHAKTNVKVKKA- 140

Query: 886  EMPSEVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIA 710
              PS V  L+ + F   V    K++LV F APWCGHCK L P +E L  T+AN+K+VVIA
Sbjct: 141  --PSNVVDLSPSNFDSVVLDKSKNVLVEFYAPWCGHCKKLMPDYEILGNTYANEKDVVIA 198

Query: 709  KVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGTHRVV 530
            K+D +A ++KA   + GV  +PT+KWF   SK+   YE GR    F+++IN++AG +RV 
Sbjct: 199  KIDCDAADNKAICSKYGVTGFPTLKWFGKQSKDGEKYEQGRDLDTFINYINKQAGVNRVK 258

Query: 529  GGGLDNVAGTVESLDTLVAKXXXXXXXXXXXXXXXXXXEGLTDAAQ---KTYAEYYVRVF 359
            GG L   AG VE LDT+  +                    + D+     +    YYV+V 
Sbjct: 259  GGKLAVGAGRVEQLDTIATEFIAAAAEVRKELVKKAQT--VVDSLPEELRIEGSYYVKVM 316

Query: 358  DKLSSNN-DWVSKELGRLDGILAKGGLAPSKRDQIQQKTNVLRKF 227
              ++  + D+V+ E+ R+   L  G ++  K D+  +K N+L  F
Sbjct: 317  KTIAEKSIDFVTTEIARITK-LVSGSMSGKKADEFAKKLNILESF 360



>sp|O13811|PDI2_SCHPO PUTATIVE PROTEIN DISULFIDE ISOMERASE C17H9.14C PRECURSOR
 pir||T37880 probable protein disulfide-isomerase (EC 5.3.4.1) - fission yeast
            (Schizosaccharomyces pombe)
 emb|CAB11223.1| (Z98597) putative protein disulfide isomerase (EC 5.3.4.1)
            [Schizosaccharomyces pombe]
          Length = 359

 Score =  231 bits (590), Expect = 8e-60
 Identities = 126/337 (37%), Positives = 196/337 (57%), Gaps = 3/337 (0%)
 Frame = -3

Query: 1234 VIELLPSN-FDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVD 1058
            V+EL   N  ++ +  S K  L+EF+A WCGHCK LAPV+E+L   +E     V I K+D
Sbjct: 22   VVELQSLNELENTIRASKKGALIEFYATWCGHCKSLAPVYEELGALFED-HNDVLIGKID 80

Query: 1057 ADAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMP 878
            AD H ++  ++ I GFPTL +F    ++P +Y + RD++SLT F++EKTG+K K+K+ +P
Sbjct: 81   ADTHSDVADKYHITGFPTLIWFPPDGSEPVQYSNARDVDSLTQFVSEKTGIK-KRKIVLP 139

Query: 877  SEVTYLNDATFSKTVGSD-KHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVD 701
            S V  L+   F K V  D K +LV F A WCG+CK LAPT+E L   F N+ NV I K++
Sbjct: 140  SNVVELDSLNFDKVVMDDKKDVLVEFYADWCGYCKRLAPTYETLGKVFKNEPNVEIVKIN 199

Query: 700  AEAPNSKATAEQQGVKSYPTIKWFPAGSKE-AVAYESGRTEQAFVDWINEKAGTHRVVGG 524
            A+         +  V S+PTIK+FP   K+    YE  R+ ++ +++IN+K+GT R   G
Sbjct: 200  ADVFADIGRLHE--VASFPTIKFFPKDDKDKPELYEGDRSLESLIEYINKKSGTQRSPDG 257

Query: 523  GLDNVAGTVESLDTLVAKXXXXXXXXXXXXXXXXXXEGLTDAAQKTYAEYYVRVFDKLSS 344
             L + AG + + D   A+                    L D+++  + +YY +VF+K+ +
Sbjct: 258  TLLSTAGRIPTFDEFAAEFLDMSNAAKEVVLEKVKQLALEDSSR--WTKYYKKVFEKILN 315

Query: 343  NNDWVSKELGRLDGILAKGGLAPSKRDQIQQKTNVLRKFV 224
            + +WV KE  RL  +L +  +A +  D  + + N+L  F+
Sbjct: 316  DENWVHKEAKRLSKLLRQKSIALASADDFKTRLNILNSFL 355



>sp|O22263|PDA6_ARATH PROBABLE PROTEIN DISULFIDE ISOMERASE A6 PRECURSOR (P5)
 pir||T00437 probable protein disulfide-isomerase (EC 5.3.4.1) precursor -
            Arabidopsis thaliana
 gb|AAC62863.1| (AC002535) putative protein disulfide-isomerase [Arabidopsis
            thaliana]
          Length = 361

 Score =  225 bits (574), Expect = 6e-58
 Identities = 133/337 (39%), Positives = 193/337 (56%), Gaps = 3/337 (0%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L   +F+  V K  K  LVEF+APWCGHCKKLAP +E L  +++ AK  V IAKVD 
Sbjct: 25   VVVLTDDSFEKEVGKD-KGALVEFYAPWCGHCKKLAPEYEKLGASFKKAKS-VLIAKVDC 82

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPS 875
            D  + +  ++G+ G+PT+++F   S +P++Y+  R+ E+L  ++  K G  + K   +P 
Sbjct: 83   DEQKSVCTKYGVSGYPTIQWFPKGSLEPQKYEGPRNAEALAEYV-NKEGGTNVKLAAVPQ 141

Query: 874  EVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDA 698
             V  L    F + V   +K +LV F APWCGHCK+LAPT+E +A  F  ++ VVIA +DA
Sbjct: 142  NVVVLTPDNFDEIVLDQNKDVLVEFYAPWCGHCKSLAPTYEKVATVFKQEEGVVIANLDA 201

Query: 697  EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGTHRVVGGGL 518
            +A   KA  E+ GV  +PT+K+FP  +K    Y+ GR    FV +INEK+GT R   G L
Sbjct: 202  DA--HKALGEKYGVSGFPTLKFFPKDNKAGHDYDGGRDLDDFVSFINEKSGTSRDSKGQL 259

Query: 517  DNVAGTVESLDTLVAKXXXXXXXXXXXXXXXXXXEGLTDAAQKT-YAEYYVRVFDK-LSS 344
             + AG VESLD LV +                  E  T     T Y + Y+++    +  
Sbjct: 260  TSKAGIVESLDALVKELVAASEDEKKAVLSRIEEEASTLKGSTTRYGKLYLKLAKSYIEK 319

Query: 343  NNDWVSKELGRLDGILAKGGLAPSKRDQIQQKTNVLRKFV 224
             +D+ SKE  RL  +L K  ++P K D++  K N+L  FV
Sbjct: 320  GSDYASKETERLGRVLGK-SISPVKADELTLKRNILTTFV 358



 Score =  114 bits (286), Expect = 1e-24
 Identities = 59/133 (44%), Positives = 80/133 (59%), Gaps = 1/133 (0%)
 Frame = -3

Query: 874 EVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDAE 695
           +V  L D +F K VG DK  LV F APWCGHCK LAP +E L A+F   K+V+IAKVD +
Sbjct: 24  DVVVLTDDSFEKEVGKDKGALVEFYAPWCGHCKKLAPEYEKLGASFKKAKSVLIAKVDCD 83

Query: 694 APNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGTHRVVGGGLD 515
               K+   + GV  YPTI+WFP GS E   YE  R  +A  +++N++ GT+  +     
Sbjct: 84  --EQKSVCTKYGVSGYPTIQWFPKGSLEPQKYEGPRNAEALAEYVNKEGGTNVKLAAVPQ 141

Query: 514 NVAG-TVESLDTLV 476
           NV   T ++ D +V
Sbjct: 142 NVVVLTPDNFDEIV 155



>sp|P38661|ERP5_MEDSA PROBABLE PROTEIN DISULFIDE ISOMERASE P5 PRECURSOR
 pir||T09614 probable protein disulfide-isomerase (EC 5.3.4.1) precursor,
            glucose-regulated [similarity] - alfalfa
 gb|AAB46930.1| (M80235) glucose-regulated endoplasmic reticular protein precursor
            [Medicago sativa]
          Length = 364

 Score =  222 bits (566), Expect = 5e-57
 Identities = 130/336 (38%), Positives = 192/336 (56%), Gaps = 3/336 (0%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L   NF+  V    K  LVEF+APWCGHCKKLAP +E L N+++ AK  V IAKVD 
Sbjct: 31   VVVLTEENFEKEV-GHDKGALVEFYAPWCGHCKKLAPEYEKLPNSFKKAKS-VLIAKVDC 88

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPS 875
            D H+ +  ++G+ G+PT+++F   S +P++++  R  ESL  F+  + G  + K    PS
Sbjct: 89   DEHKSVCSKYGVSGYPTIQWFPKGSLEPKKFEGPRTAESLAEFVNTEGGT-NVKIATAPS 147

Query: 874  EVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDA 698
             V  L   TF++ V    K +LV F APWCGHCK+LAP +E +AA F ++ +VVIA +DA
Sbjct: 148  HVVVLTPETFNEVVLDGTKDVLVEFYAPWCGHCKSLAPIYEKVAAVFKSEDDVVIANLDA 207

Query: 697  EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGTHRVVGGGL 518
            +    +  AE+  V  +PT+K+FP G+K    Y  GR    FV +INEK+GT R   G L
Sbjct: 208  D--KYRDLAEKYDVSGFPTLKFFPKGNKAGEDYGGGRDLDDFVAFINEKSGTSRDAKGQL 265

Query: 517  DNVAGTVESLDTLVAK-XXXXXXXXXXXXXXXXXXEGLTDAAQKTYAEYYVRVFDK-LSS 344
             + AG VE LD LV +                       + +   Y + Y++V  K L  
Sbjct: 266  TSEAGIVEDLDELVKEFVAANDEEKKAVFARIEEEVKKLEGSASRYGKIYLKVSKKYLEK 325

Query: 343  NNDWVSKELGRLDGILAKGGLAPSKRDQIQQKTNVLRKF 227
             +D+   E+ RL+ +L K  ++P+K D++  K N+L  +
Sbjct: 326  GSDYAKNEIQRLERLLEK-SISPAKADELTLKKNILSTY 363



 Score =  107 bits (267), Expect = 2e-22
 Identities = 51/112 (45%), Positives = 69/112 (61%)
 Frame = -3

Query: 874 EVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDAE 695
           +V  L +  F K VG DK  LV F APWCGHCK LAP +E L  +F   K+V+IAKVD +
Sbjct: 30  DVVVLTEENFEKEVGHDKGALVEFYAPWCGHCKKLAPEYEKLPNSFKKAKSVLIAKVDCD 89

Query: 694 APNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGTH 539
               K+   + GV  YPTI+WFP GS E   +E  RT ++  +++N + GT+
Sbjct: 90  --EHKSVCSKYGVSGYPTIQWFPKGSLEPKKFEGPRTAESLAEFVNTEGGTN 139



>pir||T03644 probable protein disulfide-isomerase (EC 5.3.4.1) precursor - common
            tobacco
 emb|CAA72092.1| (Y11209) protein disulfide-isomerase precursor [Nicotiana tabacum]
          Length = 359

 Score =  221 bits (562), Expect = 1e-56
 Identities = 126/336 (37%), Positives = 191/336 (56%), Gaps = 3/336 (0%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L   NF+  + +  +  LVEF+APWCGHCKKLAP +E L  ++  AK  + I KVD 
Sbjct: 26   VVVLTEENFEKEIGQD-RAALVEFYAPWCGHCKKLAPEYEKLGASFRKAKS-ILIGKVDC 83

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPS 875
            D H+ +  ++G+QG+PT+++F   S +P++Y+ GR  E+L  F+  + G  + K    PS
Sbjct: 84   DEHKSVCSKYGVQGYPTIQWFPKGSLEPKKYEGGRTAEALAEFVNSEGGT-NVKIASTPS 142

Query: 874  EVTYLNDATFSKTVGSD-KHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDA 698
             V  L+   F + V  + K +LV F APWCGHCK+LAP +E +A +F  +++VVIA +DA
Sbjct: 143  SVVVLSPDNFDEIVLDETKDVLVEFYAPWCGHCKSLAPIYEKVATSFKQEEDVVIANLDA 202

Query: 697  EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGTHRVVGGGL 518
            +    +   E+ GV  +PT+K+FP G+K    Y+ GR    FV++INEK+GT R   G  
Sbjct: 203  D--KHRDLGEKYGVSGFPTLKFFPKGNKAGEHYDGGRHLYDFVNFINEKSGTSRDSKGQF 260

Query: 517  DNVAGTVESLDTLVAK-XXXXXXXXXXXXXXXXXXEGLTDAAQKTYAEYYVRVF-DKLSS 344
               AG VESLDTLV +                    G  +     Y + Y++     +  
Sbjct: 261  TLNAGIVESLDTLVNEFVSATNEEKKAVFSKMEDEAGKLNGFAARYGKIYLKAAKSSMEK 320

Query: 343  NNDWVSKELGRLDGILAKGGLAPSKRDQIQQKTNVLRKF 227
              D+   E+ RL+ +LAK  ++P+K D+   K N+L  F
Sbjct: 321  GADYAKNEIQRLERMLAK-SISPAKSDEFTLKKNILATF 358



 Score =  114 bits (284), Expect = 3e-24
 Identities = 51/115 (44%), Positives = 72/115 (62%)
 Frame = -3

Query: 883 MPSEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKV 704
           +  +V  L +  F K +G D+  LV F APWCGHCK LAP +E L A+F   K+++I KV
Sbjct: 22  LAEDVVVLTEENFEKEIGQDRAALVEFYAPWCGHCKKLAPEYEKLGASFRKAKSILIGKV 81

Query: 703 DAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGTH 539
           D +    K+   + GV+ YPTI+WFP GS E   YE GRT +A  +++N + GT+
Sbjct: 82  DCD--EHKSVCSKYGVQGYPTIQWFPKGSLEPKKYEGGRTAEALAEFVNSEGGTN 134



>gb|AAK50038.2| (AF363787) protein disulfide isomerase family member [Aspergillus
            fumigatus]
          Length = 364

 Score =  181 bits (459), Expect = 1e-44
 Identities = 128/348 (36%), Positives = 177/348 (50%), Gaps = 8/348 (2%)
 Frame = -3

Query: 1291 LIKSFVLGXXXXXXXXXXAVIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWED 1112
            L+ +  +            V+ L   +F D  +K     L EF+APWCGHCK LAP +E+
Sbjct: 11   LLGASAVASADATADTTSDVVSLTKDSFKDF-MKEHDLVLAEFYAPWCGHCKALAPKYEE 69

Query: 1111 LANTYESAKGK-VQIAKVDADAHRELGKRFGIQGFPTLKFFDGK-SAKPEEYKSGRDLES 938
             A      KGK + + KVD     +L K  G++G    K   G  ++KP  Y+  R L  
Sbjct: 70   AAT---ELKGKNIPLVKVDCTEEEDLCKENGVEGILLSKNLRGPDNSKP--YQGARRLTR 124

Query: 937  LTTF---IAEKTGVKSKKKLEMPSEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLA 767
            L++    +  + GVK +     P++V  LND  F       + +  AF APWCGHCK LA
Sbjct: 125  LSSTWKTVPTRRGVKVRTSRLEPTKVMDLNDVLFGGPSVGGEDVQAAFYAPWCGHCK-LA 183

Query: 766  PTWEDLAAT-FANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESG 590
            P +++LAA  FA   +VV+ KVDA+  N+ AT    GV  +PTIK+    S E+V    G
Sbjct: 184  PKYDELAAAYFALHPDVVVKKVDAKIDNTNATVPDYGVSGFPTIKFSFKVSTESVDVNHG 243

Query: 589  RTEQAFVDWINEKAGTHRVVGGGLDNVAGTVESLDTLVAKXXXXXXXXXXXXXXXXXXEG 410
            R+EQ FV ++NEK G  R VGG LD  AGT+     LV                      
Sbjct: 244  RSEQDFVSFLNEKTGIPRTVGGLLDATAGTIALAQNLVPSIKPVTSHAKAASELEDVYAL 303

Query: 409  LTDAAQKTYAEYYVRVFD-KLSSNNDWVSKE-LGRLDGILAKGGLAPSKRDQIQQK 248
               AA K YA YY++V D +LS    +  KE   RL+ IL KG     K+D+ ++K
Sbjct: 304  KYSAALK-YARYYLKVEDEELSKLEKYAIKEGAARLEVILIKGRSNILKKDEFEEK 358



>gb|AAF45013.1|AE003406_218 (AE003416) symbol=BG:DS09218.4; cDNA=method:''sim4'',
            score:''1000.0'', desc:''LD05503 LD Drosophila
            melanogaster embryo BlueScript Drosophila melanogaster
            cDNA clone, full length mRNA sequence from BDGP'';
            match=method:''BLASTX'', version:''2.0a19MP-W>
 gb|AAF53532.1| (AE003650) BG:DS09218.4 gene product [Drosophila melanogaster]
          Length = 433

 Score =  172 bits (435), Expect = 8e-42
 Identities = 104/248 (41%), Positives = 140/248 (55%), Gaps = 21/248 (8%)
 Frame = -3

Query: 1294 VLIKSFVLGXXXXXXXXXXAVIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWE 1115
            +L+ +FV+G           V+EL PSNFD  VLK     +VEF+APWCGHC+ L P ++
Sbjct: 7    ILLLAFVVGSVSAFYSPSDGVVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYK 66

Query: 1114 DLANTYESAKGKVQIAKVDADAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESL 935
             LA   ++ KG V++  V+ADA   L  +FG++GFPT+K F      P +Y   R  ++ 
Sbjct: 67   KLA---KALKGVVKVGSVNADADSTLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKA- 122

Query: 934  TTFIAEKTGVKSKKKLE-----------------MPSEVTYLNDATFSKTV-GSDKHILV 809
               IAE    + KKK++                    +V  L +  F K V  SD   LV
Sbjct: 123  ---IAEAALAEVKKKVQGVLGGGGGSSSGGSGSSSGDDVIELTEDNFDKLVLNSDDIWLV 179

Query: 808  AFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWF 629
             F APWCGHCK LAP W   A        V +  +DA A  SKA   +  V+ YPTIK+F
Sbjct: 180  EFFAPWCGHCKNLAPEWAKAAKELKG--KVKLGALDATAHQSKAA--EYNVRGYPTIKFF 235

Query: 628  PAGSK---EAVAYESGRTEQAFVDWINEK 551
            PAGSK   +A  Y+ GRT    V W ++K
Sbjct: 236  PAGSKRASDAQEYDGGRTASDIVSWASDK 264



>sp|P38660|PDA6_MESAU PROTEIN DISULFIDE ISOMERASE A6 PRECURSOR (PROTEIN DISULFIDE ISOMERASE
            P5)
 pir||S19656 protein disulfide-isomerase homolog P5 precursor - golden hamster
 emb|CAA44550.1| (X62678) P5 [Mesocricetus auratus]
          Length = 439

 Score =  159 bits (402), Expect = 5e-38
 Identities = 89/222 (40%), Positives = 125/222 (56%), Gaps = 18/222 (8%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            VIEL PSNF+  V++S    LVEF+APWCGHC++L P W+  A    + K  V++  VDA
Sbjct: 27   VIELTPSNFNREVIQSNSLWLVEFYAPWCGHCQRLTPEWKKAAT---ALKDVVKVGAVDA 83

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRD--------LESLTTFIAEK----- 914
            D H+ LG ++G+QGFPT+K F     KPE+Y+ GR         L +L   + ++     
Sbjct: 84   DKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRLSGRS 143

Query: 913  ----TGVKSKKKLEMPSEVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWEDL 749
                +G + +       +V  L D TF K V  SD   +V F APWCGHCK L P W   
Sbjct: 144  GGYSSGKQGRGDSSSKKDVIELTDDTFDKNVLDSDDVWMVEFYAPWCGHCKNLEPEWATA 203

Query: 748  AATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFV 569
            A          +     +A  ++  A + G++ +PTIK F  G +  V Y+ GRT    V
Sbjct: 204  ATEVKEQTKGKVKLAAVDATVNQVLANRYGIRGFPTIKIFQKG-EAPVDYDGGRTRSDIV 262



 Score = 68.9 bits (167), Expect = 9e-11
 Identities = 50/130 (38%), Positives = 67/130 (51%), Gaps = 1/130 (0%)
 Frame = -3

Query: 955 GRDLESLTTFIAEKTGVKSKKKLEMPSEVTYLNDATFSKTVGSDKHI-LVAFTAPWCGHC 779
           G  L S T F+A  +G+ S        +V  L  + F++ V     + LV F APWCGHC
Sbjct: 5   GFGLVSCTFFLAA-SGLYSSS-----DDVIELTPSNFNREVIQSNSLWLVEFYAPWCGHC 58

Query: 778 KTLAPTWEDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAY 599
           + L P W+  AAT   D  V +  VDA+   S     Q GV+ +PTIK F A   +   Y
Sbjct: 59  QRLTPEWKK-AATALKDV-VKVGAVDADKHQS--LGGQYGVQGFPTIKIFGANKNKPEDY 114

Query: 598 ESGRTEQAFVD 566
           + GRT +A VD
Sbjct: 115 QGGRTGEAIVD 125



>sp|Q63081|PDA6_RAT PROTEIN DISULFIDE ISOMERASE A6 PRECURSOR (PROTEIN DISULFIDE ISOMERASE
            P5) (CALCIUM-BINDING PROTEIN 1) (CABP1)
 pir||S45038 protein disulfide-isomerase homolog P5 precursor - rat  (fragment)
 emb|CAA55891.1| (X79328) CaBP1 [Rattus norvegicus]
          Length = 431

 Score =  159 bits (401), Expect = 7e-38
 Identities = 94/222 (42%), Positives = 133/222 (59%), Gaps = 21/222 (9%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            VIEL PSNF+  V++S    LVEF+APWCGHC++L P W+  A+   + K  V++  V+A
Sbjct: 18   VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAS---ALKDVVKVGAVNA 74

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRD--------LESLTTFIAEKTGVKS 899
            D H+ LG ++G+QGFPT+K F     KPE+Y+ GR         L +L   + ++ G +S
Sbjct: 75   DKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRS 134

Query: 898  ---------KKKLEMPSEVTYLNDATFSKTVGSDKHI-LVAFTAPWCGHCKTLAPTWEDL 749
                     +       +V  L D TF K V   + + +V F APWCGHCK L P W   
Sbjct: 135  GGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWA-A 193

Query: 748  AATFANDK---NVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQ 578
            AAT   ++    V +A VDA    ++  A + G+K +PTIK F  G +  V Y+ GRT  
Sbjct: 194  AATEVKEQTKGKVKLAAVDATV--NQVLASRYGIKGFPTIKIFQKG-ESPVDYDGGRTRS 250

Query: 577  AFV 569
              V
Sbjct: 251  DIV 253



 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 40/103 (38%), Positives = 56/103 (53%), Gaps = 2/103 (1%)
 Frame = -3

Query: 874 EVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDA 698
           +V  L  + F++ V  SD   LV F APWCGHC+ L P W+  A+   +     + KV A
Sbjct: 17  DVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAASALKD-----VVKVGA 71

Query: 697 -EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVD 566
             A   ++   Q GV+ +PTIK F A   +   Y+ GRT +A VD
Sbjct: 72  VNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVD 116



>dbj|BAB24354.1| (AK005989) putative [Mus musculus]
          Length = 391

 Score =  157 bits (398), Expect = 2e-37
 Identities = 88/222 (39%), Positives = 125/222 (55%), Gaps = 18/222 (8%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            VIEL PSNF+  V++S    LVEF+APWCGHC++L P W+  A    + K  V++  V+A
Sbjct: 32   VIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAAT---ALKDVVKVGAVNA 88

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRD--------LESLTTFIAEKTGVKS 899
            D H+ LG ++G+QGFPT+K F     KPE+Y+ GR         L +L   + ++ G +S
Sbjct: 89   DKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRS 148

Query: 898  ---------KKKLEMPSEVTYLNDATFSKTVGSDKHI-LVAFTAPWCGHCKTLAPTWEDL 749
                     +       +V  L D TF K V   + + +V F APWCGHCK L P W   
Sbjct: 149  GGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAA 208

Query: 748  AATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFV 569
            A          +     +A  ++  A + G+K +PTIK F  G +  V Y+ GRT    V
Sbjct: 209  ATEVKEQTKGKVKLAAVDATMNQVLASRYGIKGFPTIKIFQKG-ESPVDYDGGRTRSDIV 267



 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 2/122 (1%)
 Frame = -3

Query: 931 TFIAEKTGVKSKKKLEMPSEVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWE 755
           TF    +G+ S        +V  L  + F++ V  SD   LV F APWCGHC+ L P W+
Sbjct: 17  TFFLAVSGLYSSS-----DDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWK 71

Query: 754 DLAATFANDKNVVIAKVDA-EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQ 578
             AAT   D    + KV A  A   ++   Q GV+ +PTIK F A   +   Y+ GRT +
Sbjct: 72  K-AATALKD----VVKVGAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGE 126

Query: 577 AFVD 566
           A VD
Sbjct: 127 AIVD 130



>gb|AAH06865.1|AAH06865 (BC006865) Similar to protein disulfide isomerase-related protein
            [Mus musculus]
          Length = 440

 Score =  157 bits (398), Expect = 2e-37
 Identities = 94/222 (42%), Positives = 132/222 (59%), Gaps = 21/222 (9%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            VIEL PSNF+  V++S    LVEF+APWCGHC++L P W+  A    + K  V++  V+A
Sbjct: 27   VIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAAT---ALKDVVKVGAVNA 83

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRD--------LESLTTFIAEKTGVKS 899
            D H+ LG ++G+QGFPT+K F     KPE+Y+ GR         L +L   + ++ G +S
Sbjct: 84   DKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRS 143

Query: 898  ---------KKKLEMPSEVTYLNDATFSKTVGSDKHI-LVAFTAPWCGHCKTLAPTWEDL 749
                     +       +V  L D TF K V   + + +V F APWCGHCK L P W   
Sbjct: 144  GGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWA-A 202

Query: 748  AATFANDK---NVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQ 578
            AAT   ++    V +A VDA    ++  A + G+K +PTIK F  G +  V Y+ GRT  
Sbjct: 203  AATEVKEQTKGKVKLAAVDATV--NQVLASRYGIKGFPTIKIFQKG-ESPVDYDGGRTRS 259

Query: 577  AFV 569
              V
Sbjct: 260  DIV 262



 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 2/122 (1%)
 Frame = -3

Query: 931 TFIAEKTGVKSKKKLEMPSEVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWE 755
           TF    +G+ S        +V  L  + F++ V  SD   LV F APWCGHC+ L P W+
Sbjct: 12  TFFLAVSGLYSSS-----DDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWK 66

Query: 754 DLAATFANDKNVVIAKVDA-EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQ 578
             AAT   D    + KV A  A   ++   Q GV+ +PTIK F A   +   Y+ GRT +
Sbjct: 67  K-AATALKD----VVKVGAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGE 121

Query: 577 AFVD 566
           A VD
Sbjct: 122 AIVD 125



>ref|NP_005733.1| protein disulfide isomerase-related protein [Homo sapiens]
 ref|XP_002678.2| protein disulfide isomerase-related protein [Homo sapiens]
 sp|Q15084|PDA6_HUMAN PROTEIN DISULFIDE ISOMERASE A6 PRECURSOR (PROTEIN DISULFIDE ISOMERASE
            P5)
 pir||JC4369 P5 protein precursor - human
 dbj|BAA08450.1| (D49489) human P5 [Homo sapiens]
 gb|AAH01312.1|AAH01312 (BC001312) protein disulfide isomerase-related protein [Homo sapiens]
          Length = 440

 Score =  156 bits (395), Expect = 3e-37
 Identities = 86/222 (38%), Positives = 125/222 (55%), Gaps = 18/222 (8%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            VIEL PSNF+  V++S    LVEF+APWCGHC++L P W+  A    + K  V++  VDA
Sbjct: 27   VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAT---ALKDVVKVGAVDA 83

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRD--------LESLTTFIAEKTGVKS 899
            D H  LG ++G+QGFPT+K F     +PE+Y+ GR         L +L   + ++ G +S
Sbjct: 84   DKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRS 143

Query: 898  ---------KKKLEMPSEVTYLNDATFSKTVGSDKHI-LVAFTAPWCGHCKTLAPTWEDL 749
                     +       +V  L D +F K V   + + +V F APWCGHCK L P W   
Sbjct: 144  GGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAA 203

Query: 748  AATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFV 569
            A+         +     +A  ++  A + G++ +PTIK F  G +  V Y+ GRT    V
Sbjct: 204  ASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKG-ESPVDYDGGRTRSDIV 262



 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 43/103 (41%), Positives = 57/103 (54%), Gaps = 1/103 (0%)
 Frame = -3

Query: 874 EVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDA 698
           +V  L  + F++ V  SD   LV F APWCGHC+ L P W+  AAT   D  V +  VDA
Sbjct: 26  DVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKK-AATALKDV-VKVGAVDA 83

Query: 697 EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVD 566
           +  +S     Q GV+ +PTIK F +       Y+ GRT +A VD
Sbjct: 84  DKHHS--LGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVD 125



>gb|AAB50217.1| (U79278) protein disulfide isomerase-related protein 5 [Homo sapiens]
          Length = 421

 Score =  156 bits (394), Expect = 4e-37
 Identities = 86/222 (38%), Positives = 125/222 (55%), Gaps = 18/222 (8%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            VIEL PSNF+  V++S    LVEF+APWCGHC++L P W+  A    + K  V++  VDA
Sbjct: 8    VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAT---ALKDVVKVGAVDA 64

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRD--------LESLTTFIAEKTGVKS 899
            D H  LG ++G+QGFPT+K F     +PE+Y+ GR         L +L   + ++ G +S
Sbjct: 65   DKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRS 124

Query: 898  ---------KKKLEMPSEVTYLNDATFSKTVGSDKHI-LVAFTAPWCGHCKTLAPTWEDL 749
                     +       +V  L D +F K V   + + +V F APWCGHCK L P W   
Sbjct: 125  GGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAA 184

Query: 748  AATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFV 569
            A+         +     +A  ++  A + G++ +PTIK F  G +  V Y+ GRT    V
Sbjct: 185  ASEVKEQTKGRVKLAAVDATVNQVLASRYGIRGFPTIKIFQKG-ESPVDYDGGRTRSDIV 243



 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 43/103 (41%), Positives = 57/103 (54%), Gaps = 1/103 (0%)
 Frame = -3

Query: 874 EVTYLNDATFSKTV-GSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDA 698
           +V  L  + F++ V  SD   LV F APWCGHC+ L P W+  AAT   D  V +  VDA
Sbjct: 7   DVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKK-AATALKDV-VKVGAVDA 64

Query: 697 EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVD 566
           +  +S     Q GV+ +PTIK F +       Y+ GRT +A VD
Sbjct: 65  DKHHS--LGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVD 106



>gb|AAF40463.1|AC004809_21 (AC004809) Strong simialrity to the disulfide isomerase precursor
            homolog T21L14.14 gi|2702281 from A. thaliana on BAC
            gb|AC003033. [Arabidopsis thaliana]
          Length = 443

 Score =  153 bits (386), Expect = 4e-36
 Identities = 90/228 (39%), Positives = 127/228 (55%), Gaps = 20/228 (8%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V++L PSNF   VL S    LVEFFAPWCGHC+ L P WE +A+T    KG   +A +DA
Sbjct: 30   VLQLTPSNFKSKVLNSNGVVLVEFFAPWCGHCQSLTPTWEKVAST---LKGIATVAAIDA 86

Query: 1054 DAHRELGKRFGIQGFPTLK-FFDGKSAKPEEYKSGRDLESLTTFIAEKT----------- 911
            DAH+ + + +G++GFPT+K F  GK   P +Y+  RD +S++ F  ++            
Sbjct: 87   DAHKSVSQDYGVRGFPTIKVFVPGK--PPIDYQGARDAKSISQFAIKQIKALLKDRLDGK 144

Query: 910  -------GVKSKKKLEMPSEVTYLNDATFSKTVGSDKHI-LVAFTAPWCGHCKTLAPTWE 755
                   G  S+KK   PS    LN + F + V   K + +V F APWCGHCK LAP W+
Sbjct: 145  TSGTKNGGGSSEKKKSEPSASVELNSSNFDELVTESKELWIVEFFAPWCGHCKKLAPEWK 204

Query: 754  DLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQA 575
              A        +     DAE    ++   +  V+ +PTI  F +     V YE  R+  A
Sbjct: 205  KAANNLKGKVKLGHVNCDAE----QSIKSRFKVQGFPTILVFGSDKSSPVPYEGARSASA 260

Query: 574  FVDWINEK 551
               +  E+
Sbjct: 261  IESFALEQ 268



 Score =  103 bits (256), Expect = 4e-21
 Identities = 52/124 (41%), Positives = 75/124 (59%)
 Frame = -3

Query: 1231 IELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDAD 1052
            +EL  SNFD++V +S +  +VEFFAPWCGHCKKLAP W+  AN   + KGKV++  V+ D
Sbjct: 166  VELNSSNFDELVTESKELWIVEFFAPWCGHCKKLAPEWKKAAN---NLKGKVKLGHVNCD 222

Query: 1051 AHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPSE 872
            A + +  RF +QGFPT+  F    + P  Y+  R   ++ +F  E+    +      P+E
Sbjct: 223  AEQSIKSRFKVQGFPTILVFGSDKSSPVPYEGARSASAIESFALEQLESNAG-----PAE 277

Query: 871  VTYL 860
            VT L
Sbjct: 278  VTEL 281



>gb|AAF48082.2| (AE003487) CG1837 gene product [Drosophila melanogaster]
          Length = 416

 Score =  148 bits (374), Expect = 9e-35
 Identities = 91/243 (37%), Positives = 127/243 (51%), Gaps = 10/243 (4%)
 Frame = -3

Query: 1231 IELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDAD 1052
            +EL P  FD  +  +G    V+FFAPWCGHCK++ P+WE LA        KV IAKVD  
Sbjct: 40   VELDPETFDTAI--AGGNVFVKFFAPWCGHCKRIQPLWEQLAEIMNVDNPKVIIAKVDCT 97

Query: 1051 AHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKL-EMPS 875
             H+ L     + G+PTL+ F     +  ++K  RDL ++T FI ++    ++  L E+  
Sbjct: 98   KHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLPAITDFINKELSAPAEADLGEVKR 157

Query: 874  E---------VTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKN 722
            E         V  L + TF+K V +  H  V F APWC HC+ LAPTWEDLA     +  
Sbjct: 158  EQVENLNIGKVVDLTEDTFAKHVSTGNH-FVKFFAPWCSHCQRLAPTWEDLAKELIKEPT 216

Query: 721  VVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAGT 542
            V I+K+D      ++  +   VK YPT+ W   G K+   Y   R      D    K   
Sbjct: 217  VTISKID--CTQFRSICQDFEVKGYPTLLWIEDG-KKIEKYSGAR------DLSTLKTYV 267

Query: 541  HRVVGGGLDNVAG 503
             ++VG  L+  AG
Sbjct: 268  EKMVGVPLEKTAG 280



 Score =  132 bits (331), Expect = 9e-30
 Identities = 80/196 (40%), Positives = 111/196 (55%), Gaps = 21/196 (10%)
 Frame = -3

Query: 1171 VEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHRELGKRFGIQGFPTLKFF 992
            V+FFAPWC HC++LAP WEDLA      +  V I+K+D    R + + F ++G+PTL + 
Sbjct: 187  VKFFAPWCSHCQRLAPTWEDLAKELIK-EPTVTISKIDCTQFRSICQDFEVKGYPTLLWI 245

Query: 991  -DGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKL-----------EMPSEVTYLNDAT 848
             DGK  K E+Y   RDL +L T++ +  GV  +K             E+  E       T
Sbjct: 246  EDGK--KIEKYSGARDLSTLKTYVEKMVGVPLEKTAGEAGDEKVVIEEVAGEEDAAKKLT 303

Query: 847  FSKTVGSDKH--------ILVAFTAPWCGHCKTLAPTWEDLAA-TFANDKNVVIAKVDAE 695
              +  G D+           + F APWCGHC+ L PTWE LA  T     +V IAKVD  
Sbjct: 304  PQQLTGEDEFDQAIAEGVAFIKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDCT 363

Query: 694  APNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRT 584
            AP +K     Q V+ YPT+  +  G ++   YE  R+
Sbjct: 364  APENKQVCIDQQVEGYPTLFLYKNGQRQN-EYEGSRS 399



 Score = 70.1 bits (170), Expect = 4e-11
 Identities = 34/88 (38%), Positives = 52/88 (58%), Gaps = 2/88 (2%)
 Frame = -3

Query: 1171 VEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADA--HRELGKRFGIQGFPTLK 998
            ++F+APWCGHC+KL P WE LA     A+  V+IAKVD  A  ++++     ++G+PTL 
Sbjct: 324  IKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDCTAPENKQVCIDQQVEGYPTL- 382

Query: 997  FFDGKSAKPEEYKSGRDLESLTTFIAEKTG 908
            F      +  EY+  R L  L  ++ +  G
Sbjct: 383  FLYKNGQRQNEYEGSRSLPELQAYLKKFLG 412



>pir||T01115 hypothetical protein T21L14.14 - Arabidopsis thaliana
 gb|AAB91984.1| (AC003033) putative protein disulfide isomerase [Arabidopsis
            thaliana]
          Length = 440

 Score =  147 bits (370), Expect = 3e-34
 Identities = 89/227 (39%), Positives = 122/227 (53%), Gaps = 17/227 (7%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V++L  SNF   VL S    LVEFFAPWCGHCK L P WE +AN     KG   +A +DA
Sbjct: 32   VVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKALTPTWEKVANI---LKGVATVAAIDA 88

Query: 1054 DAHRELGKRFGIQGFPTLK-FFDGKSAKPEEYKSGRDLESLTTFI--------------- 923
            DAH+   + +GI+GFPT+K F  GK+  P +Y+  RD +S+  F                
Sbjct: 89   DAHQSAAQDYGIKGFPTIKVFVPGKA--PIDYQGARDAKSIANFAYKQIKGLLSDRLEGK 146

Query: 922  AEKTGVKSKKKLEMPSEVTYLNDATFSK-TVGSDKHILVAFTAPWCGHCKTLAPTWEDLA 746
            ++ TG  SK+K   PS    LN + F    + S++  +V F APWCGHCK LAP W+  A
Sbjct: 147  SKPTGGGSKEKKSEPSASVELNASNFDDLVIESNELWIVEFFAPWCGHCKKLAPEWKRAA 206

Query: 745  ATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVD 566
                    +     D E    ++   +  V+ +PTI  F         YE  R+  A   
Sbjct: 207  KNLQGKVKLGHVNCDVE----QSIMSRFKVQGFPTILVFGPDKSSPYPYEGARSASAIES 262

Query: 565  WINE 554
            + +E
Sbjct: 263  FASE 266



>sp|P34329|PDA4_CAEEL PROBABLE PROTEIN DISULFIDE ISOMERASE A4 PRECURSOR (ERP-72 HOMOLOG)
          Length = 618

 Score =  144 bits (364), Expect = 1e-33
 Identities = 86/200 (43%), Positives = 109/200 (54%), Gaps = 2/200 (1%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L   NFD   LK     LV+F+APWCGHCK LAP +E       S+K  + +AKVDA
Sbjct: 38   VVVLTDKNFDAF-LKKNPSVLVKFYAPWCGHCKHLAPEYEKA-----SSKVSIPLAKVDA 91

Query: 1054 DAHRELGKRFGIQGFPTLKFF-DGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMP 878
                ELGKRF IQG+PTLKF+ DGK   P +Y  GRD   +  ++  +     K     P
Sbjct: 92   TVETELGKRFEIQGYPTLKFWKDGKG--PNDYDGGRDEAGIVEWVESRVDPNYKPP---P 146

Query: 877  SEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATF-ANDKNVVIAKVD 701
             EV  L    F   + +++ +LV F APWCGHCK LAP +E  A    A    V + KVD
Sbjct: 147  EEVVTLTTENFDDFISNNELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVD 206

Query: 700  AEAPNSKATAEQQGVKSYPTIK 635
            A       T  + GV  YPT+K
Sbjct: 207  ATIEKDLGT--KYGVSGYPTMK 226



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 41/114 (35%), Positives = 70/114 (60%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L   NFDD +  + +  LVEF+APWCGHCKKLAP +E  A   ++   KV++ KVDA
Sbjct: 149  VVTLTTENFDDFI-SNNELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVDA 207

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKK 893
               ++LG ++G+ G+PT+K    ++ +  +Y   R+   +  ++ +++   +KK
Sbjct: 208  TIEKDLGTKYGVSGYPTMKII--RNGRRFDYNGPREAAGIIKYMTDQSKPAAKK 259



 Score = 88.6 bits (218), Expect = 1e-16
 Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 1/109 (0%)
 Frame = -3

Query: 1216 SNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHREL 1037
            SNFD IV    K  L+EF+APWCGHCK     + +LA   +  +  V +AK+DA  + + 
Sbjct: 507  SNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPNVVLAKMDATIN-DA 565

Query: 1036 GKRFGIQGFPTLKFFD-GKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKK 890
              +F ++GFPT+ F   GK ++P +Y   RDLE L  F+  K GVKS +K
Sbjct: 566  PSQFAVEGFPTIYFAPAGKKSEPIKYSGNRDLEDLKKFMT-KHGVKSFQK 614



 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 38/112 (33%), Positives = 58/112 (50%)
 Frame = -3

Query: 886 EMPSEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAK 707
           EM   V  L D  F   +  +  +LV F APWCGHCK LAP +E  ++      ++ +AK
Sbjct: 33  EMDEGVVVLTDKNFDAFLKKNPSVLVKFYAPWCGHCKHLAPEYEKASSKV----SIPLAK 88

Query: 706 VDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEK 551
           VDA         ++  ++ YPT+K++  G K    Y+ GR E   V+W+  +
Sbjct: 89  VDATVETE--LGKRFEIQGYPTLKFWKDG-KGPNDYDGGRDEAGIVEWVESR 137



 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 59/176 (33%), Positives = 94/176 (52%), Gaps = 15/176 (8%)
 Frame = -3

Query: 1114 DLANTYESAKGKVQIAKVDADAHR--ELGKR-FGIQGFPTLKFFDGKS--AKPEEYKSGR 950
            ++A  Y+  K K  +A  +  A    ELG    G++    +  +DGK     P+E+    
Sbjct: 409  NIAQKYQKDKYKFAVADEEEFAKELEELGLGDSGLEHNVVVFGYDGKKYPMNPDEFDGEL 468

Query: 949  DLESLTTFIAEKTGVKSK---KKLEMPSE----VTYLNDATFSKTVGSD-KHILVAFTAP 794
            D E+L  F+ + +  K+K   K    P +    V  +  + F K V  + K +L+ F AP
Sbjct: 469  D-ENLEAFMKQISSGKAKAHVKSAPAPKDDKGPVKTVVGSNFDKIVNDESKDVLIEFYAP 527

Query: 793  WCGHCKTLAPTWEDLAATFANDK-NVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGS 617
            WCGHCK+    + +LA      + NVV+AK+DA   ++ +   Q  V+ +PTI + PAG 
Sbjct: 528  WCGHCKSFESKYVELAQALKKTQPNVVLAKMDATINDAPS---QFAVEGFPTIYFAPAGK 584

Query: 616  K-EAVAYESGR 587
            K E + Y   R
Sbjct: 585  KSEPIKYSGNR 595



>pir||S44756 probable protein disulfide-isomerase (EC 5.3.4.1) - Caenorhabditis
            elegans
 gb|AAA27952.1| (L15188) Hypothetical protein C14B9.2 [Caenorhabditis elegans]
          Length = 664

 Score =  144 bits (364), Expect = 1e-33
 Identities = 86/200 (43%), Positives = 109/200 (54%), Gaps = 2/200 (1%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L   NFD   LK     LV+F+APWCGHCK LAP +E       S+K  + +AKVDA
Sbjct: 84   VVVLTDKNFDAF-LKKNPSVLVKFYAPWCGHCKHLAPEYEKA-----SSKVSIPLAKVDA 137

Query: 1054 DAHRELGKRFGIQGFPTLKFF-DGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMP 878
                ELGKRF IQG+PTLKF+ DGK   P +Y  GRD   +  ++  +     K     P
Sbjct: 138  TVETELGKRFEIQGYPTLKFWKDGKG--PNDYDGGRDEAGIVEWVESRVDPNYKPP---P 192

Query: 877  SEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATF-ANDKNVVIAKVD 701
             EV  L    F   + +++ +LV F APWCGHCK LAP +E  A    A    V + KVD
Sbjct: 193  EEVVTLTTENFDDFISNNELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVD 252

Query: 700  AEAPNSKATAEQQGVKSYPTIK 635
            A       T  + GV  YPT+K
Sbjct: 253  ATIEKDLGT--KYGVSGYPTMK 272



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 41/114 (35%), Positives = 70/114 (60%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L   NFDD +  + +  LVEF+APWCGHCKKLAP +E  A   ++   KV++ KVDA
Sbjct: 195  VVTLTTENFDDFI-SNNELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVDA 253

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKK 893
               ++LG ++G+ G+PT+K    ++ +  +Y   R+   +  ++ +++   +KK
Sbjct: 254  TIEKDLGTKYGVSGYPTMKII--RNGRRFDYNGPREAAGIIKYMTDQSKPAAKK 305



 Score = 88.6 bits (218), Expect = 1e-16
 Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 1/109 (0%)
 Frame = -3

Query: 1216 SNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHREL 1037
            SNFD IV    K  L+EF+APWCGHCK     + +LA   +  +  V +AK+DA  + + 
Sbjct: 553  SNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPNVVLAKMDATIN-DA 611

Query: 1036 GKRFGIQGFPTLKFFD-GKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKK 890
              +F ++GFPT+ F   GK ++P +Y   RDLE L  F+  K GVKS +K
Sbjct: 612  PSQFAVEGFPTIYFAPAGKKSEPIKYSGNRDLEDLKKFMT-KHGVKSFQK 660



 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 38/112 (33%), Positives = 58/112 (50%)
 Frame = -3

Query: 886 EMPSEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAK 707
           EM   V  L D  F   +  +  +LV F APWCGHCK LAP +E  ++      ++ +AK
Sbjct: 79  EMDEGVVVLTDKNFDAFLKKNPSVLVKFYAPWCGHCKHLAPEYEKASSKV----SIPLAK 134

Query: 706 VDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEK 551
           VDA         ++  ++ YPT+K++  G K    Y+ GR E   V+W+  +
Sbjct: 135 VDATVETE--LGKRFEIQGYPTLKFWKDG-KGPNDYDGGRDEAGIVEWVESR 183



 Score = 68.6 bits (166), Expect = 1e-10
 Identities = 59/176 (33%), Positives = 94/176 (52%), Gaps = 15/176 (8%)
 Frame = -3

Query: 1114 DLANTYESAKGKVQIAKVDADAHR--ELGKR-FGIQGFPTLKFFDGKS--AKPEEYKSGR 950
            ++A  Y+  K K  +A  +  A    ELG    G++    +  +DGK     P+E+    
Sbjct: 455  NIAQKYQKDKYKFAVADEEEFAKELEELGLGDSGLEHNVVVFGYDGKKYPMNPDEFDGEL 514

Query: 949  DLESLTTFIAEKTGVKSK---KKLEMPSE----VTYLNDATFSKTVGSD-KHILVAFTAP 794
            D E+L  F+ + +  K+K   K    P +    V  +  + F K V  + K +L+ F AP
Sbjct: 515  D-ENLEAFMKQISSGKAKAHVKSAPAPKDDKGPVKTVVGSNFDKIVNDESKDVLIEFYAP 573

Query: 793  WCGHCKTLAPTWEDLAATFANDK-NVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGS 617
            WCGHCK+    + +LA      + NVV+AK+DA   ++ +   Q  V+ +PTI + PAG 
Sbjct: 574  WCGHCKSFESKYVELAQALKKTQPNVVLAKMDATINDAPS---QFAVEGFPTIYFAPAGK 630

Query: 616  K-EAVAYESGR 587
            K E + Y   R
Sbjct: 631  KSEPIKYSGNR 641



>pir||T27039 hypothetical protein Y49E10.4 - Caenorhabditis elegans
 emb|CAB11548.1| (Z98866) predicted using Genefinder~contains similarity to Pfam
            domain: PF00085 (Thioredoxin), Score=289.0,
            E-value=2.2e-86, N=2~cDNA EST yk228f8.3 comes from this
            gene~cDNA EST yk467h11.3 comes from this gene~cDNA EST
            yk228f8.5 comes from this gene~cD>
          Length = 436

 Score =  139 bits (350), Expect = 6e-32
 Identities = 93/270 (34%), Positives = 142/270 (52%), Gaps = 17/270 (6%)
 Frame = -3

Query: 1279 FVLGXXXXXXXXXXAVIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANT 1100
            F +           +V EL  SNFD  VLKS +  +VEF+AP+CGHCK L P ++  A  
Sbjct: 11   FAISGSSTFYTAKDSVFELTDSNFDAKVLKSDRIWIVEFYAPYCGHCKSLVPEYKKAA-- 68

Query: 1099 YESAKGKVQIAKVDADAHRELGKRFGIQGFPTLKFFDG-KSAKPEEYKSGRDL------- 944
             +  KG  +I  +DA  H+++  ++ I+G+PT+K F   + +KP +Y   R         
Sbjct: 69   -KLLKGIAEIGAIDATVHQKIPLKYSIKGYPTIKIFGATEKSKPIDYNGPRTAKGIADAV 127

Query: 943  -----ESLTTFIAEKTGVKSKKKLEMPSEVTYLNDATFSKTV-GSDKHILVAFTAPWCGH 782
                 +SL   +  K+  KSKK  +   +V  L D+ F K V  S +  +V F APWCGH
Sbjct: 128  KKSIEKSLEQRLKGKSSEKSKKS-DKKGKVVVLTDSNFDKLVLNSKEPWMVEFFAPWCGH 186

Query: 781  CKTLAPTWEDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAG---SKE 611
            C+ L P W+  A        V    +DA A  S   A++ G++ +PTIK+F  G   + +
Sbjct: 187  CQKLEPEWKKAAEEMGG--RVKFGALDATAHES--IAQKFGIRGFPTIKFFAPGTSSASD 242

Query: 610  AVAYESGRTEQAFVDWINEKAGTHRVVGGGLDNVAGTVESLDTLVAK 470
            A  Y+ GRT    + +   K   +   G   + V GT +++   V K
Sbjct: 243  AEDYQGGRTSTDLISYAESK---YDDFGAAPEVVEGTGKAVVETVCK 286



>sp|Q11067|PDA6_CAEEL PROBABLE PROTEIN DISULFIDE ISOMERASE A6 PRECURSOR
 pir||T15352 hypothetical protein B0403.4 - Caenorhabditis elegans
 gb|AAC47065.1| (U40411) Similar to protein disulfide-isomerase. [Caenorhabditis
            elegans]
          Length = 440

 Score =  137 bits (346), Expect = 2e-31
 Identities = 85/229 (37%), Positives = 122/229 (53%), Gaps = 25/229 (10%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+EL  +NF   V+ S    +VEF+APWCGHCK L P ++  A+   + KG  ++  VD 
Sbjct: 26   VVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAAS---ALKGVAKVGAVDM 82

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLT--------TFIAEKTGVKS 899
              H+ +G  + +QGFPTLK F     KP +Y   R  +++           ++ + G KS
Sbjct: 83   TQHQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQAIADSVLAEAKKAVSARLGGKS 142

Query: 898  KKKLEMPS--------------EVTYLNDATFSKTVGSDKHI-LVAFTAPWCGHCKTLAP 764
                   S              EV  L DA F   V + K I LV F APWCGHCK+L P
Sbjct: 143  SGSSSSGSGSGSGKRGGGGSGNEVVELTDANFEDLVLNSKDIWLVEFFAPWCGHCKSLEP 202

Query: 763  TWEDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGS--KEAVAYESG 590
             W+  A+       V +  +DA        A +  ++ +PTIK+F  GS   +A  Y+ G
Sbjct: 203  QWKAAASELKG--KVRLGALDATV--HTVVANKFAIRGFPTIKYFAPGSDVSDAQDYDGG 258

Query: 589  RTEQAFVDWINEKA 548
            R     V W + +A
Sbjct: 259  RQSSDIVAWASARA 272



>ref|NP_004902.1| protein disulfide isomerase related protein (calcium-binding protein,
            intestinal-related) [Homo sapiens]
 sp|P13667|PDA4_HUMAN PROTEIN DISULFIDE ISOMERASE A4 PRECURSOR (PROTEIN ERP-72) (ERP72)
 pir||A23723 protein disulfide-isomerase (EC 5.3.4.1) ERp72 precursor - human
 gb|AAA58460.1| (J05016) protein disulfide isomerase-related protein [Homo sapiens]
 gb|AAH00425.1|AAH00425 (BC000425) protein disulfide isomerase related protein
            (calcium-binding protein, intestinal-related) [Homo
            sapiens]
 gb|AAH01928.1|AAH01928 (BC001928) protein disulfide isomerase related protein
            (calcium-binding protein, intestinal-related) [Homo
            sapiens]
 gb|AAH06344.1|AAH06344 (BC006344) protein disulfide isomerase related protein
            (calcium-binding protein, intestinal-related) [Homo
            sapiens]
          Length = 645

 Score =  133 bits (334), Expect = 4e-30
 Identities = 83/230 (36%), Positives = 118/230 (51%), Gaps = 2/230 (0%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L  +NFD+ V       L+EF+APWCGHCK+ AP +E +AN  +     + +AK+DA
Sbjct: 64   VLVLNDANFDNFVADKDT-VLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDA 122

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPS 875
             +   L  RF + G+PT+K    K  +  +Y+  R  E +   + E     S+     P 
Sbjct: 123  TSASVLASRFDVSGYPTIKIL--KKGQAVDYEGSRTQEEIVAKVRE----VSQPDWTPPP 176

Query: 874  EVT-YLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFA-NDKNVVIAKVD 701
            EVT  L    F + V     ILV F APWCGHCK LAP +E  A   +     + +AKVD
Sbjct: 177  EVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVD 236

Query: 700  AEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAG 545
            A A      A++  V  YPT+K F  G      Y   R +   VD++ E++G
Sbjct: 237  ATAETD--LAKRFDVSGYPTLKIFRKG--RPYDYNGPREKYGIVDYMIEQSG 284



 Score = 97.8 bits (242), Expect = 2e-19
 Identities = 49/124 (39%), Positives = 70/124 (55%)
 Frame = -3

Query: 1225 LLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAH 1046
            L   NFD++V       LVEF+APWCGHCKKLAP +E  A         + +AKVDA A 
Sbjct: 182  LTKENFDEVV-NDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAE 240

Query: 1045 RELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPSEVT 866
             +L KRF + G+PTLK F  +  +P +Y   R+   +  ++ E++G  SK+ L +     
Sbjct: 241  TDLAKRFDVSGYPTLKIF--RKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQE 298

Query: 865  YLND 854
            +L D
Sbjct: 299  FLKD 302



 Score = 94.4 bits (233), Expect = 2e-18
 Identities = 51/110 (46%), Positives = 69/110 (62%), Gaps = 2/110 (1%)
 Frame = -3

Query: 1210 FDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHRELGK 1031
            FD IV+   K  L+EF+APWCGHCK+L PV+  LA  Y+  KG V IAK+DA A+     
Sbjct: 535  FDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLV-IAKMDATANDVPSD 593

Query: 1030 RFGIQGFPTLKFF-DGKSAKPEEYKSG-RDLESLTTFIAEKTGVKSKKKLEM 881
            R+ ++GFPT+ F   G    P +++ G RDLE L+ FI E     S+ K E+
Sbjct: 594  RYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 645



 Score = 70.1 bits (170), Expect = 4e-11
 Identities = 49/129 (37%), Positives = 72/129 (54%), Gaps = 7/129 (5%)
 Frame = -3

Query: 976 KPEEYKSGRDLESLTTFIAEKTG--VKSK---KKLEMPSEVTYLNDATFSKTV-GSDKHI 815
           +PEE+ S    E +T F   K    +KS+   K  + P +V      TF   V    K +
Sbjct: 489 EPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVV--GKTFDSIVMDPKKDV 546

Query: 814 LVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIK 635
           L+ F APWCGHCK L P +  LA  +   K +VIAK+DA A  +   +++  V+ +PTI 
Sbjct: 547 LIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATA--NDVPSDRYKVEGFPTIY 604

Query: 634 WFPAGSKE-AVAYESG 590
           + P+G K+  V +E G
Sbjct: 605 FAPSGDKKNPVKFEGG 620



>ref|NP_110437.1| hypothetical protein MGC3178 [Homo sapiens]
 gb|AAH01199.1|AAH01199 (BC001199) Similar to glucose regulated protein, 58 kDa [Homo
            sapiens]
          Length = 324

 Score =  130 bits (328), Expect = 2e-29
 Identities = 87/205 (42%), Positives = 116/205 (56%), Gaps = 18/205 (8%)
 Frame = -3

Query: 1228 ELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADA 1049
            EL  SNF+  V +      ++FFAPWCGHCK LAP WE LA   E ++  V+I KVD   
Sbjct: 85   ELSASNFELHVAQGDH--FIKFFAPWCGHCKALAPTWEQLALGLEHSE-TVKIGKVDCTQ 141

Query: 1048 HRELGKRFGIQGFPTLKFF-DGKSAKPEEYKSGRDLESLTTFI------AEKTGVKSKKK 890
            H EL     ++G+PTL +F DGK  K ++YK  RDLESL  ++       E    ++   
Sbjct: 142  HYELCSGNQVRGYPTLLWFRDGK--KVDQYKGKRDLESLREYVESQLQRTETGATETVTP 199

Query: 889  LEMP----------SEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLA-A 743
             E P            V  L +  F  T+ ++    + F APWCGHCKTLAPTWE+L+  
Sbjct: 200  SEAPVLAAEPEADKGTVLALTENNFDDTI-AEGITFIKFYAPWCGHCKTLAPTWEELSKK 258

Query: 742  TFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSK 614
             F     V IA+VD  A   +    +  V+ YPT+  F  G K
Sbjct: 259  EFPGLAGVKIAEVDCTA--ERNICSKYSVRGYPTLLLFRGGKK 299



 Score = 96.7 bits (239), Expect = 4e-19
 Identities = 58/156 (37%), Positives = 84/156 (53%), Gaps = 9/156 (5%)
 Frame = -3

Query: 1081 KVQIAKVDADAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTG-- 908
            KV +AKVD  AH ++    G++G+PTLK F     +  +Y+  RD ++L  ++ +     
Sbjct: 5    KVYVAKVDCTAHSDVCSAQGVRGYPTLKLFK-PGQEAVKYQGPRDFQTLENWMLQTLNEE 63

Query: 907  -VKSKKKLEMPSE------VTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDL 749
             V  + ++E PS       +  L+ + F   V    H  + F APWCGHCK LAPTWE L
Sbjct: 64   PVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHF-IKFFAPWCGHCKALAPTWEQL 122

Query: 748  AATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSK 614
            A    + + V I KVD        +  Q  V+ YPT+ WF  G K
Sbjct: 123  ALGLEHSETVKIGKVDCTQHYELCSGNQ--VRGYPTLLWFRDGKK 165



 Score = 92.4 bits (228), Expect = 8e-18
 Identities = 44/104 (42%), Positives = 64/104 (61%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L  +NFDD + +    T ++F+APWCGHCK LAP WE+L+         V+IA+VD 
Sbjct: 216  VLALTENNFDDTIAEG--ITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDC 273

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFI 923
             A R +  ++ ++G+PTL  F G   K  E+  GRDL+SL  F+
Sbjct: 274  TAERNICSKYSVRGYPTLLLFRG-GKKVSEHSGGRDLDSLHRFV 316



>gb|AAC37215.1| (L28174) disulfide-like protein [Acanthamoeba castellanii]
 prf||2024291A protein disulfide isomerase-like protein [Acanthamoeba castellanii]
          Length = 406

 Score =  130 bits (327), Expect = 3e-29
 Identities = 83/202 (41%), Positives = 112/202 (55%), Gaps = 20/202 (9%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDA 1055
            V+ L   NFD+          +EF+APWCGHCK LAPVWEDLA T   AKG +++ KVD 
Sbjct: 31   VVVLDDDNFDEHTASGD--WFLEFYAPWCGHCKNLAPVWEDLA-TQGKAKG-LRVGKVDC 86

Query: 1054 DAHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPS 875
              ++E+G RFG++G+PT+K    K  +   YK  R ++    F   ++G K+   + +P+
Sbjct: 87   TQNKEIGSRFGVKGYPTIKLL--KDNQLYAYKGARKVDDFLQF--AESGYKAVDPVPVPA 142

Query: 874  --------------------EVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWE 755
                                EV  L    F+      K   V F APWCGHCK LAPTWE
Sbjct: 143  PAVVVEEAEDVEGQTAGGAGEVQILTAENFTLATNGGKW-FVKFYAPWCGHCKNLAPTWE 201

Query: 754  DLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWF 629
              A+      N  IAKVD          +  GV+ YPT+K+F
Sbjct: 202  KAASELKGKVN--IAKVDCTTDG--FMCQLFGVRGYPTLKFF 239



 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 43/104 (41%), Positives = 57/104 (54%)
 Frame = -3

Query: 1189 SGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHRELGKRFGIQGF 1010
            +G    V+F+APWCGHCK LAP WE  A+     KGKV IAKVD      + + FG++G+
Sbjct: 177  NGGKWFVKFYAPWCGHCKNLAPTWEKAAS---ELKGKVNIAKVDCTTDGFMCQLFGVRGY 233

Query: 1009 PTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMP 878
            PTLKFF G      +Y   R++   + F   K G K     + P
Sbjct: 234  PTLKFFKG-DGLVRDYSGVREVSDFSDF--AKKGYKQATAQDYP 274



>ref|NP_006801.1| for protein disulfide isomerase-related [Homo sapiens]
 sp|Q14554|PDA5_HUMAN PROTEIN DISULFIDE ISOMERASE A5 PRECURSOR (PROTEIN DISULFIDE
            ISOMERASE-RELATED PROTEIN)
 pir||S66673 disulfide isomerase-related protein - human
 dbj|BAA08451.1| (D49490) protein disulfide isomerase-related protein (PDIR) [Homo
            sapiens]
 prf||2121279A protein disulfide isomerase-related protein [Homo sapiens]
          Length = 519

 Score =  129 bits (324), Expect = 6e-29
 Identities = 85/236 (36%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
 Frame = -3

Query: 1234 VIELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANT-YESAKGKVQIAKVD 1058
            V  L   +FD  V K     LV F APWCGHCKK+ P +E  A   +  A     +A VD
Sbjct: 278  VYHLTDEDFDQFV-KEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVD 336

Query: 1057 ADAHRELGKRFGIQGFPTLKFFDG--KSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLE 884
            A  ++ L +RF I  FPTLK+F    K A P      + LE +     E          E
Sbjct: 337  ATVNKALAERFHISEFPTLKYFKNGEKYAVPVLRTKKKFLEWMQN--PEAPPPPEPTWEE 394

Query: 883  MPSEVTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKV 704
              + V +L    F +T+   KH LV F APWC HCK + P +   A  F +D+ +  A V
Sbjct: 395  QQTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAV 454

Query: 703  DAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINE-KAGTHRVVG 527
            D     ++   +Q+ VK YPT  ++  G K A  Y+S RTE  F ++I   + G H  +G
Sbjct: 455  DCVKDKNQDLCQQEAVKGYPTFHYYHYG-KFAEKYDSDRTELGFTNYIRALREGDHERLG 513



 Score =  104 bits (259), Expect = 2e-21
 Identities = 66/218 (30%), Positives = 110/218 (50%), Gaps = 8/218 (3%)
 Frame = -3

Query: 1213 NFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIA--KVDADAHRE 1040
            +F  ++ K  KP L+ F+APWC  CK++ P ++  A      +G   +A   V +     
Sbjct: 161  DFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAAT---QLRGHAVLAGMNVYSSEFEN 217

Query: 1039 LGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAE----KTGVKSKKKLEMPSE 872
            + + + ++GFPT+ +F+      +    G   E +  ++      +  V      +    
Sbjct: 218  IKEEYSVRGFPTICYFEKGRFLFQYDNYGSTAEDIVEWLKNPQPPQPQVPETPWADEGGS 277

Query: 871  VTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFAN--DKNVVIAKVDA 698
            V +L D  F + V     +LV F APWCGHCK + P +E  A       D + V+A VDA
Sbjct: 278  VYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDA 337

Query: 697  EAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWI 560
                +KA AE+  +  +PT+K+F  G K AV     RT++ F++W+
Sbjct: 338  TV--NKALAERFHISEFPTLKYFKNGEKYAVPVL--RTKKKFLEWM 379



>sp|P38659|PDA4_RAT PROTEIN DISULFIDE ISOMERASE A4 PRECURSOR (PROTEIN ERP-72) (ERP72)
            (CALCIUM-BINDING PROTEIN 2) (CABP2)
 gb|AAA19217.1| (M86870) calcium-binding protein [Rattus norvegicus]
          Length = 643

 Score =  127 bits (318), Expect = 3e-28
 Identities = 79/223 (35%), Positives = 113/223 (50%), Gaps = 2/223 (0%)
 Frame = -3

Query: 1213 NFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHRELG 1034
            NFD+ V       L+EF+APWCGHCK+ AP +E +A+T +     + +AK+DA +   L 
Sbjct: 69   NFDNFVADKDT-VLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLA 127

Query: 1033 KRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPSEVTY-LN 857
             +F + G+PT+K    K  +  +Y   R  E +   + E     S+     P EVT  L 
Sbjct: 128  SKFDVSGYPTIKIL--KKGQAVDYDGSRTQEEIVAKVRE----VSQPDWTPPPEVTLTLT 181

Query: 856  DATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFA-NDKNVVIAKVDAEAPNSK 680
               F   V +   ILV F APWCGHCK LAP +E  A   +     + +AKVDA      
Sbjct: 182  KENFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTD- 240

Query: 679  ATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAG 545
              A++  V  YPT+K F  G      Y   R +   VD++ E++G
Sbjct: 241  -LAKRFDVSGYPTLKIFRKG--RPFDYNGPREKYGIVDYMVEQSG 282



 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 49/126 (38%), Positives = 71/126 (55%)
 Frame = -3

Query: 1231 IELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDAD 1052
            + L   NFDD+V  +    LVEF+APWCGHCKKLAP +E  A         + +AKVDA 
Sbjct: 178  LTLTKENFDDVV-NNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDAT 236

Query: 1051 AHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPSE 872
               +L KRF + G+PTLK F  +  +P +Y   R+   +  ++ E++G  SK+ L +   
Sbjct: 237  EQTDLAKRFDVSGYPTLKIF--RKGRPFDYNGPREKYGIVDYMVEQSGPPSKEILTLKQV 294

Query: 871  VTYLND 854
              +L D
Sbjct: 295  QEFLKD 300



 Score = 90.1 bits (222), Expect = 4e-17
 Identities = 49/110 (44%), Positives = 68/110 (61%), Gaps = 2/110 (1%)
 Frame = -3

Query: 1210 FDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHRELGK 1031
            FD IV+   K  L+EF+APWCGHCK+L PV+  L   Y+  K  V IAK+DA A+     
Sbjct: 533  FDAIVMDPKKDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGQKDLV-IAKMDATANDITND 591

Query: 1030 RFGIQGFPTLKFF-DGKSAKPEEYKSG-RDLESLTTFIAEKTGVKSKKKLEM 881
            R+ ++GFPT+ F   G    P +++ G RDLE L+ FI E    +S+ K E+
Sbjct: 592  RYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHATKRSRTKEEL 643



 Score = 77.0 bits (188), Expect = 3e-13
 Identities = 46/122 (37%), Positives = 66/122 (53%), Gaps = 3/122 (2%)
 Frame = -3

Query: 919 EKTGVKSKKKLEMPSE--VTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLA 746
           E+   + +  LE+  E  V  LND  F   V     +L+ F APWCGHCK  AP +E +A
Sbjct: 44  EEEDEEDEDDLEVKEENGVWVLNDENFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIA 103

Query: 745 ATFA-NDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFV 569
           +T   ND  + +AK+D  A ++   A +  V  YPTIK    G  +AV Y+  RT++  V
Sbjct: 104 STLKDNDPPIAVAKID--ATSASMLASKFDVSGYPTIKILKKG--QAVDYDGSRTQEEIV 159

Query: 568 DWINE 554
             + E
Sbjct: 160 AKVRE 164



 Score = 67.4 bits (163), Expect = 3e-10
 Identities = 34/96 (35%), Positives = 55/96 (56%), Gaps = 1/96 (1%)
 Frame = -3

Query: 823 KHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYP 644
           K +L+ F APWCGHCK L P +  L   +   K++VIAK+DA A  +  T ++  V+ +P
Sbjct: 542 KDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGQKDLVIAKMDATA--NDITNDRYKVEGFP 599

Query: 643 TIKWFPAGSKE-AVAYESGRTEQAFVDWINEKAGTHR 536
           TI + P+G K+  + +E G  +   +    ++  T R
Sbjct: 600 TIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHATKR 636



>pir||S32476 protein disulfide-isomerase (EC 5.3.4.1) ERp72 precursor - rat
          Length = 643

 Score =  127 bits (318), Expect = 3e-28
 Identities = 79/223 (35%), Positives = 113/223 (50%), Gaps = 2/223 (0%)
 Frame = -3

Query: 1213 NFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHRELG 1034
            NFD+ V       L+EF+APWCGHCK+ AP +E +A+T +     + +AK+DA +   L 
Sbjct: 69   NFDNFVADKDT-VLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLA 127

Query: 1033 KRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPSEVTY-LN 857
             +F + G+PT+K    K  +  +Y   R  E +   + E     S+     P EVT  L 
Sbjct: 128  SKFDVSGYPTIKIL--KKGQAVDYDGSRTQEEIVAKVRE----VSQPDWTPPPEVTLTLT 181

Query: 856  DATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFA-NDKNVVIAKVDAEAPNSK 680
               F   V +   ILV F APWCGHCK LAP +E  A   +     + +AKVDA      
Sbjct: 182  KENFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTD- 240

Query: 679  ATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFVDWINEKAG 545
              A++  V  YPT+K F  G      Y   R +   VD++ E++G
Sbjct: 241  -LAKRFDVSGYPTLKIFRKG--RPFDYNGPREKYGIVDYMVEQSG 282



 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 49/126 (38%), Positives = 71/126 (55%)
 Frame = -3

Query: 1231 IELLPSNFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDAD 1052
            + L   NFDD+V  +    LVEF+APWCGHCKKLAP +E  A         + +AKVDA 
Sbjct: 178  LTLTKENFDDVV-NNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDAT 236

Query: 1051 AHRELGKRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPSE 872
               +L KRF + G+PTLK F  +  +P +Y   R+   +  ++ E++G  SK+ L +   
Sbjct: 237  EQTDLAKRFDVSGYPTLKIF--RKGRPFDYNGPREKYGIVDYMVEQSGPPSKEILTLKQV 294

Query: 871  VTYLND 854
              +L D
Sbjct: 295  QEFLKD 300



 Score = 90.1 bits (222), Expect = 4e-17
 Identities = 49/110 (44%), Positives = 68/110 (61%), Gaps = 2/110 (1%)
 Frame = -3

Query: 1210 FDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHRELGK 1031
            FD IV+   K  L+EF+APWCGHCK+L PV+  L   Y+  K  V IAK+DA A+     
Sbjct: 533  FDAIVMDPKKDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGQKDLV-IAKMDATANDITND 591

Query: 1030 RFGIQGFPTLKFF-DGKSAKPEEYKSG-RDLESLTTFIAEKTGVKSKKKLEM 881
            R+ ++GFPT+ F   G    P +++ G RDLE L+ FI E    +S+ K E+
Sbjct: 592  RYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHATKRSRTKEEL 643



 Score = 77.0 bits (188), Expect = 3e-13
 Identities = 46/122 (37%), Positives = 66/122 (53%), Gaps = 3/122 (2%)
 Frame = -3

Query: 919 EKTGVKSKKKLEMPSE--VTYLNDATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLA 746
           E+   + +  LE+  E  V  LND  F   V     +L+ F APWCGHCK  AP +E +A
Sbjct: 44  EEEDEEDEDDLEVKEENGVWVLNDENFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIA 103

Query: 745 ATFA-NDKNVVIAKVDAEAPNSKATAEQQGVKSYPTIKWFPAGSKEAVAYESGRTEQAFV 569
           +T   ND  + +AK+D  A ++   A +  V  YPTIK    G  +AV Y+  RT++  V
Sbjct: 104 STLKDNDPPIAVAKID--ATSASMLASKFDVSGYPTIKILKKG--QAVDYDGSRTQEEIV 159

Query: 568 DWINE 554
             + E
Sbjct: 160 AKVRE 164



 Score = 67.4 bits (163), Expect = 3e-10
 Identities = 34/96 (35%), Positives = 55/96 (56%), Gaps = 1/96 (1%)
 Frame = -3

Query: 823 KHILVAFTAPWCGHCKTLAPTWEDLAATFANDKNVVIAKVDAEAPNSKATAEQQGVKSYP 644
           K +L+ F APWCGHCK L P +  L   +   K++VIAK+DA A  +  T ++  V+ +P
Sbjct: 542 KDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGQKDLVIAKMDATA--NDITNDRYKVEGFP 599

Query: 643 TIKWFPAGSKE-AVAYESGRTEQAFVDWINEKAGTHR 536
           TI + P+G K+  + +E G  +   +    ++  T R
Sbjct: 600 TIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHATKR 636



>ref|NP_033917.1| calcium binding protein, intestinal; endoplasmic reticulum protein 72
            [Mus musculus]
 pir||S06318 endoplasmic reticulum protein ERp72 homolog - mouse
 emb|CAA68777.1| (Y00884) 3.4J polypeptide [Mus musculus]
          Length = 584

 Score =  126 bits (317), Expect = 4e-28
 Identities = 79/223 (35%), Positives = 113/223 (50%), Gaps = 2/223 (0%)
 Frame = -3

Query: 1213 NFDDIVLKSGKPTLVEFFAPWCGHCKKLAPVWEDLANTYESAKGKVQIAKVDADAHRELG 1034
            NFD+ V       L+EF+APWCGHCK+ AP +E +A+T +     + +AK+DA +   L 
Sbjct: 31   NFDNFVADKDT-VLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLA 89

Query: 1033 KRFGIQGFPTLKFFDGKSAKPEEYKSGRDLESLTTFIAEKTGVKSKKKLEMPSEVTY-LN 857
             +F + G+PT+K    K  +  +Y   R  E +   + E     S+     P EVT  L 
Sbjct: 90   SKFDVSGYPTIKIL--KKGQAVDYDGSRTQEEIVAKVRE----VSQPDWTPPPEVTLSLT 143

Query: 856  DATFSKTVGSDKHILVAFTAPWCGHCKTLAPTWEDLAATFA-NDKNVVIAKVDAEAPNSK 680
               F   V +   ILV F APWCGHCK LAP +E  A   +     + +AKVDA      
Sbjct: 144  KDNFDDVVNNADIILVEFYAPWC