The query sequence for this search has been filtered. Filtering
eliminates low complexity regions that commonly give spuriously high
scores that reflect compositional bias rather than significant
position-by-position alignment. Filtering can eliminate these potentially
confounding matches (e.g., hits against proline-rich regions or poly-A
tails) from the blast reports, leaving regions whose blast statistics
reflect the specificity of their pairwise alignment.

BLASTX 2.2.1 [Apr-13-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 1605_G07_M13ZS5.seq 1605_G07_M13ZS5 0 0 0 1 441
         (441 letters)

Database: nr
           705,144 sequences; 222,175,239 total letters


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

gb|AAF56673.1|  (AE003759) CG6051 gene product [Drosophila m...    35  0.24
sp|P35146|AROD_BACSU  3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDR...    33  0.68
ref|NP_055548.1|  KIAA0305 gene product [Homo sapiens] >gi|2...    32  2.0
ref|XP_003699.3|  KIAA0305 gene product [Homo sapiens]             32  2.0
sp|O02008|TRA2_DROVI  TRANSFORMER-2 SEX-DETERMINING PROTEIN ...    32  2.0
pir||T37840  probable vacuolar protein - fission yeast  (Sch...    32  2.0
gb|AAF52609.1|  (AE003620) CG8506 gene product [Drosophila m...    32  2.0
pir||T49237  hypothetical protein F7K15.80 - Arabidopsis tha...    31  2.6
gb|AAC46631.1|  (U23545) Hk protein [Drosophila melanogaster]      31  2.6
gb|AAF46567.1|  (AE003449) Hk gene product [Drosophila melan...    31  2.6
gb|AAG10615.1|AC008030_15  (AC008030) Hypothetical protein [...    31  2.6
pir||T18961  FAB1 protein homolog VF11C1L.1 - Caenorhabditis...    31  2.6
pir||T40375  phosphatidylinositol-4-phosphate 5-kinase - fis...    31  3.4
gb|AAF56679.1|  (AE003759) CG6001 gene product [Drosophila m...    30  4.4
ref|NP_116674.1|  type II PI(4)P5-kinase (PIP4,5 kinase) sim...    30  4.4
sp|P34756|FAB1_YEAST  PROBABLE PHOSPHATIDYLINOSITOL-4-PHOSPH...    30  4.4
ref|NP_071735.1|  FYVE-finger-containing Rab5 effector prote...    30  4.4
dbj|BAB31910.1|  (AK019909) putative [Mus musculus]                30  4.4
ref|NP_035216.1|  phosphoinositide kinase, fyve-containing [...    30  4.4
dbj|BAB46907.1|  (AB060914) hypothetical protein [Macaca fas...    30  4.4
pir||T48578  hypothetical protein T31B5.130 - Arabidopsis th...    30  5.8
gb|AAF64468.1|AF239997_1  (AF239997) smad anchor for recepto...    30  5.8
gb|AAF46725.1|  (AE003454) Sara gene product [Drosophila mel...    30  5.8
pir||T09358  hypothetical protein F23K16.50 - Arabidopsis th...    30  5.8
sp|O06411|PIT_MYCTU  PROBABLE LOW-AFFINITY INORGANIC PHOSPHA...    30  7.6
gb|AAK44792.1|  (AE006955) phosphate transport protein [Myco...    30  7.6
pir||T17457  SARA protein - African clawed frog >gi|4092769|...    30  7.6
pir||T25148  hypothetical protein VT23B5.2 - Caenorhabditis ...    30  7.6
pir||T13576  hypothetical protein 52C10.5 - fruit fly (Droso...    30  7.6
sp|P34185|TOP1_SYNP7  DNA TOPOISOMERASE I (OMEGA-PROTEIN) (R...    30  7.6
pir||T33568  hypothetical protein R160.7 - Caenorhabditis el...    30  7.6
pir||T22532  hypothetical protein F53A2.8 - Caenorhabditis e...    30  7.6
pir||T24806  hypothetical protein T10G3.5 - Caenorhabditis e...    30  7.6
gb|AAF48305.1|  (AE003493) CG9941 gene product [Drosophila m...    30  7.6
gb|AAK46387.1|  (AE007061) polyketide synthase [Mycobacteriu...    30  7.6
pir||G70944  probable polyketide synthase Rv2048c - Mycobact...    30  7.6
gb|AAF57789.1|  (AE003802) EG:52C10.5 gene product [Drosophi...    30  7.6
ref|NP_078789.1|  FYVE and coiled-coil domain containing 1; ...    30  7.6
ref|XP_016981.1|  FYVE and coiled-coil domain containing 1 [...    30  7.6
gb|AAK52089.1|  (AY032860) EEA1 [Caenorhabditis elegans]           30  7.6
dbj|BAA34514.1|  (AB018337) KIAA0794 protein [Homo sapiens]        29  9.9
ref|NP_079434.1|  hypothetical protein FLJ22251 [Homo sapien...    29  9.9
pir||T37956  probable vacuolar protein sorting-associated pr...    29  9.9
gb|AAK50771.1|AF361055_1  (AF361055) FYVE-finger protein EIP...    29  9.9
emb|CAC17732.1|  (AJ250024) FYVE-finger containing protein [...    29  9.9
gb|AAD03047.1|  (AF098795) type I polyketide synthase; Cfa6 ...    29  9.9

>gb|AAF56673.1| (AE003759) CG6051 gene product [Drosophila melanogaster]
          Length = 920

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 15/21 (71%), Positives = 17/21 (80%), Gaps = 6/21 (28%)
 Frame = +2

Query: 53  MGCQ------RRRCHCRVCGGIWCRVC 115
           M CQ      RRR HCR CGG++C VC
Sbjct: 847 MACQTPFTAFRRRHHCRNCGGVFCGVC 873
>sp|P35146|AROD_BACSU 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE)
 pir||S45563 3-dehydroquinate dehydratase (EC 4.2.1.10) aroC - Bacillus subtilis
 gb|AAA67501.1| (L09228) dehydroquinate dehydratase [Bacillus subtilis]
 emb|CAB14240.1| (Z99116) 3-dehydroquinate dehydratase [Bacillus subtilis]
          Length = 255

 Score = 33.1 bits (74), Expect = 0.68
 Identities = 19/70 (27%), Positives = 35/70 (49%)
 Frame = +1

Query: 196 KSSDLQAVDCENFDGALSVRASLLGKSSDVTLAKPHSAFETTSRSDVSSGEVQESCVCRL 375
           ++ D+  +D E F G  +V+A        V+LA+ ++ +   S  D     V++  + RL
Sbjct: 106 QTKDIDLIDIELFSGDANVKAL-------VSLAEENNVYVVMSNHDFEKTPVKDEIISRL 158

Query: 376 RNSEDLVRYI 405
           R  +DL  +I
Sbjct: 159 RKMQDLGAHI 168
>ref|NP_055548.1| KIAA0305 gene product [Homo sapiens]
 dbj|BAA20764.1| (AB002303) KIAA0305 [Homo sapiens]
          Length = 1539

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 13/21 (61%), Positives = 16/21 (75%), Gaps = 6/21 (28%)
 Frame = +2

Query: 53  MGCQ------RRRCHCRVCGGIWCRVC 115
           M CQ      +RR HCR CG ++C VC
Sbjct: 754 MNCQVKFTFTKRRHHCRACGKVFCGVC 780
>ref|XP_003699.3| KIAA0305 gene product [Homo sapiens]
          Length = 1539

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 13/21 (61%), Positives = 16/21 (75%), Gaps = 6/21 (28%)
 Frame = +2

Query: 53  MGCQ------RRRCHCRVCGGIWCRVC 115
           M CQ      +RR HCR CG ++C VC
Sbjct: 754 MNCQVKFTFTKRRHHCRACGKVFCGVC 780
>sp|O02008|TRA2_DROVI TRANSFORMER-2 SEX-DETERMINING PROTEIN
 gb|AAB58113.1| (U72682) transformer-2 protein isoform 272 [Drosophila virilis]
          Length = 272

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 20/75 (26%), Positives = 32/75 (42%)
 Frame = -3

Query: 424 RHNCSHQYISPNPQSSANDKHNSLEPRQKKRPIYSSFRKQNEAWLASHR*IFQATMLLPT 245
           +H CSH   + +P S+A+ + +    R+    +Y S R  N    + HR   ++    P 
Sbjct: 21  KHKCSHSSATSSPSSAASSESSRTRQRRSDGEVYGS-RHNNYKSSSQHRRRSRSGSDSPQ 79

Query: 244 APHRSFRNPLPEDRM 200
             H S R      RM
Sbjct: 80  VRHYSGRTSRDRQRM 94
>pir||T37840 probable vacuolar protein - fission yeast  (Schizosaccharomyces
           pombe)
 emb|CAB16219.1| (Z99162) putative vacuolar protein [Schizosaccharomyces pombe]
          Length = 536

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 11/17 (64%), Positives = 13/17 (75%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RRR HCR+CG + CR C
Sbjct: 292 RRRRHCRLCGRVICRFC 308
>gb|AAF52609.1| (AE003620) CG8506 gene product [Drosophila melanogaster]
          Length = 505

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 11/17 (64%), Positives = 13/17 (75%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR+CGGI C  C
Sbjct: 197 RRQHHCRLCGGIMCNDC 213
>pir||T49237 hypothetical protein F7K15.80 - Arabidopsis thaliana
 emb|CAB89044.1| (AL353871) putative protein [Arabidopsis thaliana]
          Length = 485

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 11/15 (73%), Positives = 12/15 (79%)
 Frame = +2

Query: 71  RCHCRVCGGIWCRVC 115
           R HCR CGGI+CR C
Sbjct: 195 RHHCRFCGGIFCRNC 209
>gb|AAC46631.1| (U23545) Hk protein [Drosophila melanogaster]
          Length = 546

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
 Frame = -2

Query: 290 SVTSLDFPS---NDALTDSAPSKFSQSTA*RSDDFLTARRGVVDAANTRCQRLLSANFTT 120
           +VTS++ P+   +DA     P    QST       L A    +    T  Q+L+  N   
Sbjct: 73  AVTSIEMPTVVADDAGVPPLPLPLPQSTPQPLLMALPANLNFITGPTT--QQLMIGNGAM 130

Query: 119 DNIPCTKSHHRHDNDNAGADNPCEES 42
             IP T   + ++N+N   DN  +ES
Sbjct: 131 GVIPSTNDSNNNNNNNNNVDNTSDES 156
>gb|AAF46567.1| (AE003449) Hk gene product [Drosophila melanogaster]
          Length = 548

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
 Frame = -2

Query: 290 SVTSLDFPS---NDALTDSAPSKFSQSTA*RSDDFLTARRGVVDAANTRCQRLLSANFTT 120
           +VTS++ P+   +DA     P    QST       L A    +    T  Q+L+  N   
Sbjct: 73  AVTSIEMPTVVADDAGVPPLPLPLPQSTPQPLLMALPANLNFITGPTT--QQLMIGNGAM 130

Query: 119 DNIPCTKSHHRHDNDNAGADNPCEES 42
             IP T   + ++N+N   DN  +ES
Sbjct: 131 GVIPSTNDSNNNNNNNNNVDNTSDES 156
>gb|AAG10615.1|AC008030_15 (AC008030) Hypothetical protein [Arabidopsis thaliana]
          Length = 469

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 11/15 (73%), Positives = 12/15 (79%)
 Frame = +2

Query: 71  RCHCRVCGGIWCRVC 115
           R HCR CGGI+CR C
Sbjct: 211 RHHCRYCGGIFCRDC 225
>pir||T18961 FAB1 protein homolog VF11C1L.1 - Caenorhabditis elegans
 emb|CAA91791.1| (Z67879) contains similarity to Pfam domain: PF01363 (FYVE zinc
           finger), Score=60.7, E-value=3.4e-16, N=1; PF01504
           (Phosphatidylinositol-4-phosphate 5-Kinase),
           Score=-46.5, E-value=3.9e-08, N=1~cDNA EST yk88b11.5
           comes from this gene~cDNA EST yk76b6.3 >
 emb|CAA19436.1| (AL023817) contains similarity to Pfam domain: PF01363 (FYVE zinc
           finger), Score=60.7, E-value=3.4e-16, N=1; PF01504
           (Phosphatidylinositol-4-phosphate 5-Kinase),
           Score=-46.5, E-value=3.9e-08, N=1~cDNA EST yk88b11.5
           comes from this gene~cDNA EST yk76b6.>
          Length = 1375

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVCYRS 124
           RRR HCR+CG I+C  C  S
Sbjct: 20  RRRHHCRLCGQIFCAKCCSS 39
>pir||T40375 phosphatidylinositol-4-phosphate 5-kinase - fission yeast
           (Schizosaccharomyces pombe) (fragment)
 emb|CAA19005.1| (AL023534) fyve finger containing putative
           phosphatidylinositol-4-phosphate 5-kinase
           [Schizosaccharomyces pombe]
          Length = 1337

 Score = 30.8 bits (68), Expect = 3.4
 Identities = 10/19 (52%), Positives = 14/19 (73%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVCYR 121
           RR+ HCR+CG I C+ C +
Sbjct: 77  RRKHHCRICGKIICKYCLK 95
>gb|AAF56679.1| (AE003759) CG6001 gene product [Drosophila melanogaster]
          Length = 1351

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 10/17 (58%), Positives = 13/17 (75%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR CG I+C+ C
Sbjct: 880 RRKHHCRSCGEIFCKAC 896
>ref|NP_116674.1| type II PI(4)P5-kinase (PIP4,5 kinase) similar to human PIP5K-II;
           Fab1p [Saccharomyces cerevisiae]
 pir||S56274 FAB1 protein - yeast (Saccharomyces cerevisiae)
 dbj|BAA09258.1| (D50617) FAB1 protein [Saccharomyces cerevisiae]
          Length = 2278

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 10/17 (58%), Positives = 13/17 (75%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR+CG I+C  C
Sbjct: 257 RRKHHCRICGQIFCSSC 273
>sp|P34756|FAB1_YEAST PROBABLE PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE FAB1
           (1-PHOSPHATIDYLINOSITOL-4-PHOSPHATE KINASE) (PIP5K)
           (PTDINS(4)P-5-KINASE) (DIPHOSPHOINOSITIDE KINASE)
 gb|AAA81360.1| (U01017) Fab1p [Saccharomyces cerevisiae]
          Length = 2278

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 10/17 (58%), Positives = 13/17 (75%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR+CG I+C  C
Sbjct: 257 RRKHHCRICGQIFCSSC 273
>ref|NP_071735.1| FYVE-finger-containing Rab5 effector protein rabenosyn-5 [Homo
           sapiens]
 gb|AAG33246.1| (AY009133) FYVE-finger-containing Rab5 effector protein Rabenosyn-5
           [Homo sapiens]
          Length = 784

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 10/18 (55%), Positives = 13/18 (71%)
 Frame = +2

Query: 62  QRRRCHCRVCGGIWCRVC 115
           + RR HCR+CG I C+ C
Sbjct: 173 RNRRHHCRLCGSIMCKKC 190
>dbj|BAB31910.1| (AK019909) putative [Mus musculus]
          Length = 384

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 10/18 (55%), Positives = 13/18 (71%)
 Frame = +2

Query: 62  QRRRCHCRVCGGIWCRVC 115
           + RR HCR+CG I C+ C
Sbjct: 172 RNRRHHCRLCGSIMCKKC 189
>ref|NP_035216.1| phosphoinositide kinase, fyve-containing [Mus musculus]
 sp|Q9Z1T6|FYV1_MOUSE FYVE FINGER-CONTAINING PHOSPHOINOSITIDE KINASE
           (1-PHOSPHATIDYLINOSITOL-4-PHOSPHATE KINASE) (PIP5K)
           (PTDINS(4)P-5-KINASE) (P235)
 pir||T18290 FYVE finger-containing phosphoinositide kinase - mouse
 gb|AAD10191.1| (AF102777) FYVE finger-containing phosphoinositide kinase [Mus
           musculus]
          Length = 2052

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 11/17 (64%), Positives = 13/17 (75%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RRR HCR+CG I+C  C
Sbjct: 186 RRRHHCRLCGQIFCSRC 202
>dbj|BAB46907.1| (AB060914) hypothetical protein [Macaca fascicularis]
          Length = 543

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 10/18 (55%), Positives = 13/18 (71%)
 Frame = +2

Query: 62  QRRRCHCRVCGGIWCRVC 115
           + RR HCR+CG I C+ C
Sbjct: 173 RNRRHHCRLCGSIMCKKC 190
>pir||T48578 hypothetical protein T31B5.130 - Arabidopsis thaliana
 emb|CAB86638.1| (AL163491) putative protein [Arabidopsis thaliana]
          Length = 370

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 21/43 (48%), Positives = 30/43 (68%), Gaps = 11/43 (25%)
 Frame = +1

Query: 136 DKRRWQR--------VLAASTTPRLAVRKSS--DLQAVDC-ENFDGALSVRASL 264
           +KR W+R          A+S    L  +K S  DL+ +DC E+FDG  S+RAS+
Sbjct: 57  EKREWKRDSYDRDEIPCASSFDELLKQQKPSEDDLKDIDCGEDFDGVWSIRASM 110
>gb|AAF64468.1|AF239997_1 (AF239997) smad anchor for receptor activation [Drosophila
           melanogaster]
 emb|CAC37791.1| (AJ310804) Smad Anchor for Receptor Activation [Drosophila
           melanogaster]
          Length = 1343

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 10/17 (58%), Positives = 12/17 (69%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           +RR HCR CG + C VC
Sbjct: 548 KRRHHCRACGKVLCSVC 564
>gb|AAF46725.1| (AE003454) Sara gene product [Drosophila melanogaster]
          Length = 1291

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 10/17 (58%), Positives = 12/17 (69%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           +RR HCR CG + C VC
Sbjct: 548 KRRHHCRACGKVLCSVC 564
>pir||T09358 hypothetical protein F23K16.50 - Arabidopsis thaliana
 emb|CAB44677.1| (AL078620) hypothetical protein [Arabidopsis thaliana]
 emb|CAB80605.1| (AL161595) hypothetical protein [Arabidopsis thaliana]
          Length = 781

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 19/64 (29%), Positives = 32/64 (49%)
 Frame = +1

Query: 40  QLSSHGLSAPALSLSCLWWDLVQGMLSVVKLADKRRWQRVLAASTTPRLAVRKSSDLQAV 219
           QLS     AP++S +C           +V   D+R++++++ AS TP +A    + L  V
Sbjct: 434 QLSDFQNRAPSMSKTC-----------IVGSTDRRKFRKLIVASHTPLIAAVDENGLVYV 482

Query: 220 DCEN 231
            C N
Sbjct: 483 LCVN 486
>sp|O06411|PIT_MYCTU PROBABLE LOW-AFFINITY INORGANIC PHOSPHATE TRANSPORTER
 pir||D70547 probable pitA protein - Mycobacterium tuberculosis (strain H37RV)
 emb|CAB08979.1| (Z95558) pitA [Mycobacterium tuberculosis]
          Length = 417

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 15/43 (34%), Positives = 22/43 (50%), Gaps = 2/43 (4%)
 Frame = +3

Query: 147 LAASVGSVNDTTSCGQEVIRSSGSGL--RKLRWGAVGKSIVAWKI 275
           L+A  G    TT      +  SG G    ++RWG  G+ +VAW +
Sbjct: 269 LSAHFGYALSTTQVATGSVLGSGVGKPGAEVRWGVAGRMVVAWLV 313
>gb|AAK44792.1| (AE006955) phosphate transport protein [Mycobacterium tuberculosis
           CDC1551]
          Length = 417

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 15/43 (34%), Positives = 22/43 (50%), Gaps = 2/43 (4%)
 Frame = +3

Query: 147 LAASVGSVNDTTSCGQEVIRSSGSGL--RKLRWGAVGKSIVAWKI 275
           L+A  G    TT      +  SG G    ++RWG  G+ +VAW +
Sbjct: 269 LSAHFGYALSTTQVATGSVLGSGVGKPGAEVRWGVAGRMVVAWLV 313
>pir||T17457 SARA protein - African clawed frog
 gb|AAC99463.1| (AF104305) Smad anchor for receptor activation [Xenopus laevis]
          Length = 1235

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 9/17 (52%), Positives = 12/17 (69%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           +RR HCR CG ++C  C
Sbjct: 537 KRRHHCRACGKVFCAAC 553
>pir||T25148 hypothetical protein VT23B5.2 - Caenorhabditis elegans
 emb|CAB07677.1| (Z93390) contains similarity to Pfam domain: PF00400 (WD domain,
            G-beta repeat), Score=38.1, E-value=6.5e-08, N=3; PF01363
            (FYVE zinc finger), Score=115.4, E-value=1.3e-31, N=1;
            PF02138 (Beige/BEACH domain), Score=773.7,
            E-value=2.4e-229, N=1~cDNA EST >
 emb|CAA21780.1| (AL032675) contains similarity to Pfam domain: PF00400 (WD domain,
            G-beta repeat), Score=38.1, E-value=6.5e-08, N=3; PF01363
            (FYVE zinc finger), Score=115.4, E-value=1.3e-31, N=1;
            PF02138 (Beige/BEACH domain), Score=773.7,
            E-value=2.4e-229, N=1~cDNA ES>
          Length = 931

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 18/42 (42%), Positives = 22/42 (51%), Gaps = 9/42 (21%)
 Frame = +2

Query: 17   GRAYHHLTNSPHMGCQR---------RRCHCRVCGGIWCRVCYRS*SWQTR 142
            GRA H + +     C           R+ HCR CG I+C  C R  S  TR
Sbjct: 855  GRADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITR 905
>pir||T13576 hypothetical protein 52C10.5 - fruit fly (Drosophila melanogaster)
 emb|CAA22949.1| (AL035311) 1-evidence=predicted by
           content~1-method=genefinder;084~1-method_score=133.73~1-
           evidence_end~2-evidence=predicted by
           match~2-match_accession=SWISS-PROT:P34756~2-
           match_description=PROBABLE
           PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE FAB1 (EC 2.>
          Length = 1854

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 10/17 (58%), Positives = 13/17 (75%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR+CG I+C  C
Sbjct: 243 RRKHHCRLCGQIFCSKC 259
>sp|P34185|TOP1_SYNP7 DNA TOPOISOMERASE I (OMEGA-PROTEIN) (RELAXING ENZYME) (UNTWISTING
           ENZYME) (SWIVELASE)
 pir||S32158 DNA topoisomerase (EC 5.99.1.2) - Synechococcus sp
 emb|CAA51086.1| (X72391) Topoisomerase I [Synechococcus sp.]
          Length = 839

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 14/48 (29%), Positives = 21/48 (43%)
 Frame = -3

Query: 430 CVRHNCSHQYISPNPQSSANDKHNSLEPRQKKRPIYSSFRKQNEAWLA 287
           CV       Y+SP P+       N+ E  +  RP  ++FR   E  L+
Sbjct: 341 CVEQMYGKNYLSPQPRQFTTKSKNAQEAHEAIRPAGNTFRLPQETGLS 388
>pir||T33568 hypothetical protein R160.7 - Caenorhabditis elegans
 gb|AAC68738.1| (AF099001) contains similarity to a vac1/fab1-type domain
           [Caenorhabditis elegans]
          Length = 658

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 11/17 (64%), Positives = 12/17 (69%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RRR HCR CG I+C  C
Sbjct: 583 RRRHHCRNCGRIFCHKC 599
>pir||T22532 hypothetical protein F53A2.8 - Caenorhabditis elegans
 emb|CAB04456.1| (Z81546) contains similarity to Pfam domain: PF01363 (FYVE zinc
           finger), Score=28.0, E-value=5.7e-07, N=1~cDNA EST
           yk31h5.5 comes from this gene~cDNA EST yk194b11.3 comes
           from this gene~cDNA EST yk416b6.3 comes from this
           gene~cDNA EST yk194b11.5 comes >
          Length = 676

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 10/18 (55%), Positives = 13/18 (71%)
 Frame = +2

Query: 68  RRCHCRVCGGIWCRVCYR 121
           RR HC +CG I+CR C +
Sbjct: 643 RRIHCHLCGMIFCRRCLK 660
>pir||T24806 hypothetical protein T10G3.5 - Caenorhabditis elegans
 emb|CAB03330.1| (Z81118) Similarity to Human endosomal protein P162 (TR:Q15075),
            contains similarity to Pfam domain: PF01363 (FYVE zinc
            finger), Score=113.9, E-value=3.4e-31, N=1~cDNA EST
            EMBL:Z14487 comes from this gene~cDNA EST EMBL:Z14556
            comes from this gene~cDNA >
          Length = 1164

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 10/16 (62%), Positives = 12/16 (74%)
 Frame = +2

Query: 68   RRCHCRVCGGIWCRVC 115
            R+ HCRVCG I+C  C
Sbjct: 1123 RKHHCRVCGKIYCNPC 1138
>gb|AAF48305.1| (AE003493) CG9941 gene product [Drosophila melanogaster]
          Length = 789

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 9/76 (11%)
 Frame = -2

Query: 269 PSNDALTDSAPSKFSQSTA*RSDDFLTARRGVVDAANTRCQRLLSANFTTDN-------- 114
           P  D L      K+ +STA    D        VD+ N +   LLS    + N        
Sbjct: 517 PKQDKLQIVNERKYPRSTAGSGGDGSAGTDDDVDSENEKLSPLLSPGSKSKNVSSKSLKQ 576

Query: 113 -IPCTKSHHRHDNDNAGADNPCEES 42
            + C ++    DN ++  D P EES
Sbjct: 577 VVACLEADDDVDNKSSTGDGPTEES 601
>gb|AAK46387.1| (AE007061) polyketide synthase [Mycobacterium tuberculosis CDC1551]
          Length = 4151

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
 Frame = +1

Query: 49   SHGLSAPALSLSCLWWDLVQGMLSVVKLADKRRWQR--VLAASTTPRLAVRKSSDLQAVD 222
            +HGL  PA+SL    WD    M   +  AD  R  R  VLA ST   L            
Sbjct: 1844 AHGL--PAISLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEAL------------ 1889

Query: 223  CENFDGALSVRASLLGKSS-DVTLAKPHSAFETTSRSDVSS 342
             E FD A+ V    L  +  D+T  + H+       SD++S
Sbjct: 1890 -ELFDTAMIVDEPFLAPARIDLTALRAHAVAVPPMFSDLAS 1929
>pir||G70944 probable polyketide synthase Rv2048c - Mycobacterium tuberculosis
            (strain H37RV)
 emb|CAA17262.1| (AL021899) pks12 [Mycobacterium tuberculosis]
          Length = 4151

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 3/98 (3%)
 Frame = +1

Query: 49   SHGLSAPALSLSCLWWDLVQGMLSVVKLADKRRWQR--VLAASTTPRLAVRKSSDLQAVD 222
            +HGL  PA+SL    WD    M   +  AD  R  R  VLA ST   L            
Sbjct: 1844 AHGL--PAISLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEAL------------ 1889

Query: 223  CENFDGALSVRASLLGKSS-DVTLAKPHSAFETTSRSDVSS 342
             E FD A+ V    L  +  D+T  + H+       SD++S
Sbjct: 1890 -ELFDTAMIVDEPFLAPARIDLTALRAHAVAVPPMFSDLAS 1929
>gb|AAF57789.1| (AE003802) EG:52C10.5 gene product [Drosophila melanogaster]
          Length = 1809

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 10/17 (58%), Positives = 13/17 (75%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR+CG I+C  C
Sbjct: 203 RRKHHCRLCGQIFCSKC 219
>ref|NP_078789.1| FYVE and coiled-coil domain containing 1; hypothetical protein
            FLJ13335 [Homo sapiens]
 emb|CAC33883.1| (AJ292348) FYVE and coiled-coil domain containing 1 [Homo sapiens]
          Length = 1478

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 10/16 (62%), Positives = 12/16 (74%)
 Frame = +2

Query: 68   RRCHCRVCGGIWCRVC 115
            RR HCR+CG I+C  C
Sbjct: 1191 RRHHCRICGRIFCYYC 1206
>ref|XP_016981.1| FYVE and coiled-coil domain containing 1 [Homo sapiens]
          Length = 1478

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 10/16 (62%), Positives = 12/16 (74%)
 Frame = +2

Query: 68   RRCHCRVCGGIWCRVC 115
            RR HCR+CG I+C  C
Sbjct: 1191 RRHHCRICGRIFCYYC 1206
>gb|AAK52089.1| (AY032860) EEA1 [Caenorhabditis elegans]
          Length = 1205

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 10/16 (62%), Positives = 12/16 (74%)
 Frame = +2

Query: 68   RRCHCRVCGGIWCRVC 115
            R+ HCRVCG I+C  C
Sbjct: 1164 RKHHCRVCGKIYCNPC 1179
>dbj|BAA34514.1| (AB018337) KIAA0794 protein [Homo sapiens]
          Length = 490

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 21/76 (27%), Positives = 34/76 (44%)
 Frame = +1

Query: 166 ASTTPRLAVRKSSDLQAVDCENFDGALSVRASLLGKSSDVTLAKPHSAFETTSRSDVSSG 345
           +S+ P+   R  S + A +    + A  +RASL     D T  K  S  +  S S++ SG
Sbjct: 269 SSSPPKKCARSESLIDASEDSQLEAA--IRASLQETHFDSTQTKQDSRSDEESESELFSG 326

Query: 346 EVQESCVCRLRNSEDL 393
             +   VC     E++
Sbjct: 327 SEEFISVCGSDEEEEV 342
>ref|NP_079434.1| hypothetical protein FLJ22251 [Homo sapiens]
 dbj|BAB15276.1| (AK025904) unnamed protein product [Homo sapiens]
          Length = 310

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 10/17 (58%), Positives = 12/17 (69%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR CG I+C  C
Sbjct: 261 RRKHHCRNCGHIFCNTC 277
>pir||T37956 probable vacuolar protein sorting-associated protein - fission
           yeast (Schizosaccharomyces pombe)
 emb|CAB11641.1| (Z98974) putative vacuolar protein sorting-associated protein
           [Schizosaccharomyces pombe]
          Length = 610

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 9/16 (56%), Positives = 12/16 (74%)
 Frame = +2

Query: 68  RRCHCRVCGGIWCRVC 115
           R+ HCR CGG++C  C
Sbjct: 188 RKHHCRNCGGVFCNQC 203
>gb|AAK50771.1|AF361055_1 (AF361055) FYVE-finger protein EIP1 [Homo sapiens]
          Length = 600

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 10/17 (58%), Positives = 12/17 (69%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR CG I+C  C
Sbjct: 551 RRKHHCRNCGHIFCNTC 567
>emb|CAC17732.1| (AJ250024) FYVE-finger containing protein [Mus musculus]
          Length = 600

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 10/17 (58%), Positives = 12/17 (69%)
 Frame = +2

Query: 65  RRRCHCRVCGGIWCRVC 115
           RR+ HCR CG I+C  C
Sbjct: 551 RRKHHCRNCGHIFCNTC 567
>gb|AAD03047.1| (AF098795) type I polyketide synthase; Cfa6 [Pseudomonas syringae]
          Length = 2731

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 16/38 (42%), Positives = 19/38 (49%)
 Frame = +1

Query: 67   PALSLSCLWWDLVQGMLSVVKLADKRRWQRVLAASTTP 180
            PA SL+  WW  V G+ S +  AD  R  R   A  TP
Sbjct: 2467 PATSLAWGWWQPVTGLSSRLTAADNARIARTGFAPITP 2504
Database: nr Posted date: Jun 30, 2001 11:40 PM Number of letters in database: 222,175,239 Number of sequences in database: 705,144 Lambda K H 0.315 0.127 0.00 Gapped Lambda K H 0.267 0.0410 4.94e-324 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 178,900,197 Number of Sequences: 705144 Number of extensions: 3589656 Number of successful extensions: 11156 Number of sequences better than 10.0: 92 Number of HSP's better than 10.0 without gapping: 10834 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 11149 length of database: 222,175,239 effective HSP length: 107 effective length of database: 146,724,831 effective search space used: 5722268409 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits)